The children of the original characters could be the main ones. For instance, Riley and Lucas's child could be a central character. They would inherit some of their parents' traits but also have their own unique personalities.
New students who move into the neighborhood and befriend the kids of the original characters could also be main characters. They could bring in different perspectives and cultures, adding more depth to the story. For example, a character from another country who has a very different upbringing but still finds common ground with the others.
The children of Iron Man and Pepper Potts could be main characters. They might inherit Tony's intelligence and use it to create new and advanced technology for the team. Maybe they have some sort of armored suit as well.
Boruto, of course, is an obvious choice as he is Naruto's son. He already has a lot of development in the official series, but in a fanfic, you could explore his growth in different directions, like if he had to take on a much greater responsibility at a younger age.
The children of the main Fairy Tail characters like Natsu and Lucy's kid, or Gray and Juvia's offspring could be main characters. They would inherit some of their parents' powers and personalities.
The children of Blair and Chuck would be great main characters. They could inherit their parents' charm, ambition, and love for power plays. Maybe they would be rivals at first but then gradually realize they have more in common than they thought.
The children of Serena and Dan could be main characters. Maybe a daughter who has her mother's charm and her father's love for writing. She could be torn between the glamorous Upper East Side life and her own artistic pursuits.
Most likely, the main characters from the next generation of the wizarding world, like the children of Harry Potter and his friends. And of course, the Dursleys.
Potential main characters could be the descendants of the van der Woodsen and Bass families. A young Bass who is trying to make a name for himself in the business world while also dealing with the family's dark past. Then there could be a van der Woodsen girl who is rebelling against the family's high - society norms. Additionally, a new character from a different background who moves to the Upper East Side and befriends these heirs could also be a main character, adding an element of freshness to the story.
One idea could be that the new generation faces a school crisis, like a strict new rule that they think is unfair. They could start a peaceful protest to change it, just like the old characters might have.
Well, in a 'Girl Meets World' fanfic, the main characters would typically include Cory and Topanga's daughter, Riley. Her best friend Maya would also be a central figure. And of course, there's Farkle, who is an important part of their group. There might also be other characters from the original 'Boy Meets World' series making appearances in the fanfic, like Shawn Hunter.
The children of Nagisa and Kayano could be main characters. They might inherit some of their parents' skills and quirks. For example, Nagisa's son could have his father's stealthy nature.