Who would be the main antagonist in a 'Harry Potter meets Nightwing' fanfiction?

It could be a power - hungry alien leader who wants to take over Hogwarts and use its magic for their own empire.

A dark wizard from the Harry Potter universe could be the main antagonist. Maybe a follower of Voldemort who escaped the final battle and found his way to Byakko's world. He sees the power of Byakko and wants to use it for his own evil purposes. He could try to enslave Byakko and use its power to take over both the wizarding world and Byakko's realm.

Most likely, Medusa would be the main antagonist. Her ability to turn people to stone makes her a very dangerous foe for Harry Potter and the other characters in the wizarding world.

It could be a dark fairy who wants to use the power of both the wizarding world and Pixie Hollow for her own evil purposes. She might try to steal the magic from Hogwarts and the pixie dust from Pixie Hollow to become all - powerful.

It could be a descendant of a rival family to the Peverells. This person might be jealous of the power and secrets that the Peverell family held and wants to stop Harry from uncovering them. They could try to manipulate events to their advantage and create obstacles for Harry.

It could be Aku. Since he is the main villain in Samurai Jack's world, his power and evil nature would make him a great antagonist. He could see Harry's magic as a threat and try to eliminate him. And if he teams up with some of the dark forces from the Harry Potter universe like Voldemort or the Death Eaters, it would be even more challenging for Harry and Jack.

There could be a group of dark wizards who are working together to bring chaos to the wizarding world. They target Amelia Bones because of her position in the Ministry and Harry Potter because of his fame. This group, with their evil intentions and powerful dark magic, would serve as the main antagonists in the fanfiction.

The main antagonist might be a being from another dimension who is able to manipulate both magic and the Hulk's gamma - irradiated energy. This being wants to use the chaos caused by the meeting of Harry and the Hulk to open a portal to let in more of his kind to take over all the universes. He sets traps for Harry and the Hulk and constantly tries to keep them from working together to stop him.

Perhaps a rogue Overwatch agent who has turned against the organization. When Harry arrives, this agent sees an opportunity. He believes that by using Harry's magic, he can take over Overwatch and rule the world. So he tries to manipulate Harry and turn him against Tracer and the rest of the good - hearted Overwatch members.

It could still be Voldemort. Even though the focus is on Harry and Nagini, Voldemort is Nagini's master and the main source of evil in the Harry Potter world. He would likely try to stop Harry from getting too close to Nagini or from finding out any secrets Nagini might hold.