One possible plot could be that Naruto's sister constantly tries to protect him from all dangers. She might follow him on his missions secretly, getting into all sorts of comical and dangerous situations herself. For example, she could end up interfering in a fight between Naruto and a villain in a way that both annoys and endears her to Naruto.
In the fanfic, her obsession could manifest in her always trying to be like Naruto. She copies his ninja techniques, tries to dress like him, and even attempts to mimic his mannerisms. This could cause some confusion among their friends and comrades, but also bring out some interesting character development as Naruto has to deal with having a mini - me in the form of his sister.
Maybe she is obsessed with collecting every little memento related to Naruto. So she has a room full of his old kunai, headbands he's outgrown, and pictures she's drawn of him. This obsession could lead to some light - hearted family drama as Naruto is a bit embarrassed by her over - the - top behavior but also realizes it comes from a place of love.
Maybe Itachi, despite his stoic nature, starts to have an unexpected soft spot for Sakura. He could be secretly protecting her during her missions, which might lead to some tense and mysterious moments as Sakura tries to figure out who her mysterious protector is.
Naruto might be initially confused. He's used to being the one chasing after recognition and friends, so having his sister be so obsessed with him would be a new experience. He could be a bit awkward around her at first.
One possible plotline could be that Naruto's sister secretly helps him during his difficult times in the village. Maybe she provides him with extra training resources or helps him outwit the bullies without him knowing it's her at first.
One possibility is that the snakes could be a source of new powers for Naruto. Maybe they could help him in stealth missions, slithering through tight spaces and gathering intelligence. For example, he could use the snakes' ability to sense vibrations to detect hidden enemies.
One possible motive could be jealousy. Maybe she was jealous of Naruto's growing power and popularity within the village. Another reason might be related to some dark family secret or a curse that forces her to take his life against her will.
One possible plot could be that Anko uses her skills and knowledge to protect Naruto from the very beginning. Since she's his sister, she might be more involved in his training at a younger age. Maybe she teaches him some of her unique jutsu privately, which gives Naruto an edge over his peers. For example, she could teach him some of her snake - related jutsu, which Naruto could then modify to fit his own style.
It could be that in an alternate universe within the fanfic, Naruto's parents didn't die. But they had to give him up for some reason. As Naruto grows up and becomes a hero, they see his journey from afar. They regret their decision deeply because they realize they missed out on his life and all the things they could have done as a family.
Well, it could start with the sister having some sort of jealousy or resentment towards Naruto. Maybe she feels overshadowed by him, so she starts to abuse him verbally or physically. Naruto, being the kind - hearted character he is, might initially be confused and hurt, but as the story progresses, he could start to fight back against this unjust treatment, either by trying to reason with her or by becoming stronger to protect himself.
A simple plot could be that Fem Orochimaru wants to use Naruto's chakra for her own gain. She tries to capture him but Naruto always manages to escape. Each encounter makes her more obsessed as she realizes how powerful Naruto truly is.
One possible plot could be that Lucy is a long - lost sister of Naruto. She has been living in a different village all this time and has unique ninja abilities. When they finally meet, they have to work together to face a common enemy that threatens both their villages.