A great plot could involve a time - travel element. Koro - sensei accidentally sends the students back in time to the era of KHR. The students get involved with the Vongola family's affairs. Some of the students might form bonds with the younger versions of the Guardians. They could use their knowledge from the future (like assassination techniques and scientific knowledge) to help the Vongola in a difficult situation, while also trying to find a way back to their own time.
One possible plot could be that the students from Assassination Classroom are sent on a mission to the world of KHR. They could end up having to help the Guardians in a battle against a new and powerful enemy. Tsuna and his friends would be initially suspicious of these strange new allies but soon realize their skills and unique abilities can be of great help.
Definitely Nagisa. In the crossover, he could be the one who has the hardest time adapting to the new world of KHR. His assassin skills would be put to the test in a different way compared to Assassination Classroom. He might form an interesting friendship with Tsuna, as both are somewhat timid at first but have great potential within them.
Another storyline could involve a character from Assassination Classroom being sent to the KHR world. Nagisa, with his assassin skills, could get involved in the mafia - like affairs of the KHR universe. He might use his stealth and combat abilities to help out the good guys in that world, or perhaps he gets caught in the middle of a power struggle between different mafia families.
Maybe there's a powerful dark magic that is threatening both the KHR world and the Fairy Tail world. So, the Vongola Family decides to team up with Fairy Tail. Tsuna could bond with Natsu over their determination to protect their friends and families. The two groups would combine their unique powers. Like, Reborn's assassination skills along with Erza's swordsmanship could create a really cool battle strategy against the common enemy.
The plot could center around Nagisa's relationships with the female students in the class. Since she has now become a girl, she might form a closer bond with them. They could start a girl - only club or group within the class where they share secrets and train together. However, this could also lead to some jealousy or conflict from the male students. Nagisa would then have to navigate through these relationship issues while still focusing on the main goal of assassinating Korosensei.
One possible plot could be a student from the future traveling back to the time of the Assassination Classroom. They might use their knowledge of the future events in the classroom to change certain outcomes. For example, they could try to prevent some of the students from getting into dangerous situations during their attempts to assassinate Koro - sensei.
One idea could be an OC who has a unique ability related to stealth. For example, they can blend into the shadows like a chameleon. This OC could use this ability to get closer to Koro - sensei without being detected, adding a new dynamic to the assassination attempts. Another plot could involve an OC who is a transfer student from a different school with a completely different teaching style. They struggle to adapt to the chaos of Class 3 - E at first but eventually find their place and contribute to the assassination plans in their own way. Maybe an OC who is a master of disguise and uses it to trick Koro - sensei into various situations where they can try to attack him.
Well, a possible plot could be that Nagisa, as a girl, discovers new powers or abilities that are related to her femininity. Maybe she has a special intuition that helps the class in their assassination attempts. The story could also focus on her love life. She might develop feelings for a new character or perhaps Karma in a different way than in the original story. There could be a lot of drama as she tries to balance her feelings with her duties as an assassin in training.
First, understand the personalities of the characters from both KHR and Assassination Classroom. For example, Reborn from KHR is a strict and somewhat mysterious tutor, while Koro - sensei is a fun - loving but deadly octopus - teacher. When creating an interaction, think about how their different traits would clash or complement each other. Maybe Reborn would be intrigued by Koro - sensei's unique abilities and try to find a way to use them for his own training methods.
A plot could revolve around a time - travel aspect. A student accidentally travels back in time to before Koro - sensei was experimented on and tries to change the course of events. This would involve a lot of moral dilemmas as they might be changing the future for better or worse.
Well, you could write a fanfiction where the students develop new and unique assassination techniques. It could also be interesting to write about a time - travel plot, where a student goes back in time to change something that would affect the whole assassination classroom scenario. Or perhaps a story that focuses on the relationship between Koro - sensei and a particular student, like Nagisa, and how it develops in unexpected ways.