Harry Potter and Ron Weasley are great best friends in fiction. They go through a lot together at Hogwarts, from facing magical creatures to battling dark wizards. Their friendship is full of loyalty, humor and they support each other no matter what.
Sherlock Holmes and Dr. Watson. Watson is Holmes' loyal companion. He helps Holmes in his investigations, not just by providing practical assistance but also by being someone Holmes can bounce ideas off of. Their friendship is based on mutual respect and a shared interest in solving mysteries.
Frodo Baggins and Samwise Gamgee from 'The Lord of the Rings'. Sam is Frodo's steadfast friend throughout their perilous journey to destroy the One Ring. He endures many hardships, always looking out for Frodo and even carrying him when he is too weak to continue. Their friendship is a symbol of true loyalty and self - sacrifice.