Perhaps a powerful and unknown shinobi from a far - off land. This shinobi has heard of Team 7's reputation and sees them as a threat to his plans of world domination. He uses his unique and mysterious jutsu to challenge Team 7 at every turn, and they have to figure out his motives and weaknesses to stop him.
It could be Orochimaru. He has always been interested in Sasuke and might target ANBU Team 7 to get to him. Orochimaru's experiments and his desire for power make him a formidable and menacing villain. He could also be using some new jutsu or have created more powerful minions to fight against Team 7.
Maybe in the fanfic, Team 7 in ANBU is tasked with protecting a powerful and important shinobi from another village who has come to Konoha for peace negotiations. Naruto tries to befriend the visiting shinobi, Sasuke is constantly on guard against any possible threats, and Sakura is ready to heal any injuries in case of an attack. There could be internal conflicts within Team 7 as they deal with different approaches to protection.
You might consider adding Tenten to the team. She has a vast knowledge of weapons which could be handy in various missions. And Kiba, with Akamaru by his side, could offer enhanced senses and tracking abilities for the Anbu team.
Perhaps a powerful shinobi from another village who has a special grudge against the Leaf's ANBU. He targets Kakashi and Naruto specifically because of their reputation within the ANBU. He has unique abilities that pose a great challenge to them, like the ability to nullify ninjutsu for short periods.
The main antagonist could be an old - school ninja who believes in the traditional and often harsh ways of the ANBU. They see Naruto's actions as weakening the village and set out to oppose him at every turn, trying to bring back the old ANBU regime.
Well, one major plot change could be in the power dynamics. Since Naruto in Anbu is likely more skilled and experienced. He might take a more dominant role in Team 7's missions. For example, he could quickly assess and handle dangerous situations that the original Team 7 might struggle with. This could also change the relationships within the team. Sasuke might be more competitive towards Naruto, seeing him as an even greater rival. And Sakura might have more admiration or fear towards Naruto because of his Anbu status.
A new character could be introduced as the main villain. This character could be someone from an ancient clan that was once in control of the 10 - tailed beast but lost it. Now, seeing Naruto with that power, they want it back and will stop at nothing to get it. They could have unique powers and abilities that make them a formidable foe for Naruto and his friends.
It could be a new character, a powerful dark wizard who wants to use the combined power of Naruto's chakra and Pikachu's electricity for his own evil purposes. He creates all sorts of dark creatures and sends them after Naruto and Pikachu to try and capture them. He's very cunning and has a lot of minions to do his bidding.
It could be a rogue Anbu member. This person might be jealous of Naruto's power and popularity within the Anbu. So, they spread false rumors about Naruto which lead to his decision to leave the village. This antagonist would then try to further harm Naruto while he's outside the village, using their own Anbu skills against him.
There's also a chance that the main character could be a completely new character from a minor clan in the Naruto universe. This character could have some hidden bloodline limit that makes them a prodigy in the ANBU. They might start as an underdog but quickly rise through the ranks due to their exceptional skills and intelligence.