Perhaps there could be a plot where the ninja villages in Naruto's world are in a state of chaos due to a mysterious force. Saitama, being the hero he is, stumbles into this world and is initially confused. Naruto sees Saitama's strength and asks for his help. Along the way, Saitama starts to understand the concept of ninja and chakra, and Naruto learns about Saitama's simple yet effective way of life. They bond over their shared goal of restoring peace to the ninja world.
A cool plot might be that the villains from both universes join forces. Orochimaru could be interested in the scientific research done in the One Punch Man world to create artificial monsters. Meanwhile, some of the more intelligent monsters in One Punch Man might want to use Orochimaru's knowledge of jutsu and immortality techniques. Naruto and Saitama would then have to work together, with Naruto using his strategic mind and Saitama's raw power to take on this combined threat.
One idea could be that Naruto and Saitama somehow end up in a shared dimension where they have to team up to defeat a common enemy. For example, a powerful demon from Naruto's world that has the ability to regenerate like some of the monsters in One Punch Man's world. Another plot could involve Naruto learning Saitama's training regime and trying to incorporate it into his own ninja training, while Saitama is intrigued by Naruto's chakra system and tries to figure out if he can use it to make his punches even more powerful.