One possible plot could be Sonic accidentally getting hit by a strange energy beam during a battle with Dr. Eggman. This beam could have some sort of mutagenic effect that slowly starts to transform him into a human. As he turns into a human, he has to deal with the loss of his super speed at first. He then has to adapt to living as a human while still trying to protect his friends and the world from Eggman's new threats.
In a 'Sonic turns into a human' fanfiction, it could start with Sonic finding a mysterious artifact. When he touches it, it starts a transformation process. As a human, Sonic has to rely on his wits more than his speed. He could join a group of human resistance fighters against Eggman, who has launched a new type of attack that Sonic in his hedgehog form couldn't have countered. This new form gives him a different perspective on the fight and he uses his human abilities, like climbing and using human - made tools, to outsmart Eggman.
Maybe in the fanfiction, Sonic enters a magical realm where the laws of his world don't apply. There, a powerful wizard mistakes him for a threat and casts a spell on him that turns him human. Sonic, now in human form, has to find a way to convince the wizard to reverse the spell. Along the way, he discovers new things about himself and forms new relationships with the inhabitants of the magical realm, all while his friends from his world are desperately searching for him.
The fanfiction could go like this. Sonic is on a mission in a spooky, abandoned town. Unbeknownst to him, it's infested with vampires. One of them manages to turn him into a vampire. At first, Sonic is horrified. His appearance changes slightly, with paler fur and redder eyes. He has to learn to live with his new condition. His friends like Tails and Knuckles are confused and a bit scared. However, Sonic discovers that being a vampire gives him the ability to sense danger from afar. He then uses this to his advantage to protect the town and his friends from an even greater evil that's lurking in the shadows. Eventually, he might find a way to reverse the transformation and return to his normal self.
The plot might involve Sonic being turned into a Pokemon by a powerful wizard in the Pokemon universe. As a Pokemon, he retains some of his speed abilities but also has to learn Pokemon moves. He meets a group of friendly Pokemon trainers who help him understand this new world. Together, they enter Pokemon battles against other trainers and gym leaders, all while Sonic tries to find a way back to his own world.
Dr. Eggman would be an obvious choice. Since Sonic is now in a more vulnerable human form, Eggman could see this as the perfect opportunity to finally defeat Sonic and take over the world. He might come up with new devious plans, like creating robots specifically designed to target a human Sonic.
One possible plot could be that Sonic, after being exposed to a strange Chaos Emerald malfunction, turns into a girl. As a girl, Sonic might face new challenges in terms of her identity. For example, her friends like Tails and Knuckles might initially be confused. Sonic could then have to deal with different reactions from her enemies too. Maybe Dr. Eggman would underestimate her in this new form, but she would prove him wrong by using her speed and skills in new and unexpected ways. She might also discover new aspects of her own personality that were hidden before the transformation.
Well, the plot could start with a young mechanic who is always around cars. One day, while working on a very special vintage car, there's a strange energy surge. The next thing he knows, he is the car. He experiences life from a different perspective. He can't speak in the traditional sense but tries to convey messages through his headlights and horn. He discovers he has new senses, like being able to detect mechanical problems in other cars just by being near them. He goes on a journey to find a way to turn back into a human while having many encounters with different people and cars along the way.
Maybe in the fanfiction, there's a scientific experiment gone wrong. A human scientist was trying to find a way to bridge the gap between humans and monsters. Sans, being a curious skeleton, volunteered to be a part of the experiment. However, instead of just creating a connection, the experiment transforms Sans into a human. As a human, he experiences new emotions more intensely, like hunger and fatigue, which he didn't really have as a skeleton. He then uses his new human form to try and convince other humans that monsters are not to be feared.
A 'sonic turns into a girl' fanfic could have a plot where an evil villain casts a spell on Sonic to turn him into a girl as part of a devious plan. Sonic, now in a female form, has to find a way to break the spell. Along the way, Sonic realizes that being a girl gives her new insights into the challenges that female characters in her world face. For example, she might notice how some areas are less accessible or how she is treated differently by some characters, which could lead to a story about equality as well as Sonic's quest to return to his normal form.
Well, one possible plot could be that Sans discovers a mysterious magic spell or artifact that gradually transforms him into a human. As he changes, he has to deal with new sensations like feeling pain and hunger in a more intense way. He also might struggle with how other characters in the Undertale world view him now that he's different.
One possible plot twist could be that Saphira, as a human, has to relearn all her dragon skills in a human form. For example, she might have to find new ways to use her strength or her senses which were so much more powerful as a dragon. Another twist could be that she has to hide her true identity from other humans who might fear or try to use her if they knew she was once a dragon.
Well, one possible plot could be that the alien is conducting some sort of experiment on Earth. It sees humans as interesting subjects and decides to transform a human into a cow as part of its study on different species' behaviors. Maybe it wants to see how the human mind copes with being in the body of a cow, like how it interacts with other cows and its reaction to the simple life of a cow.