Since I don't have prior knowledge of this 'kathleen noise graphic novel', it could be that Kathleen is an artist or a musician and the 'noise' refers to the creative process. The graphic novel could then be about her journey in creating art or music, with all the distractions and inspirations that come with it, which are depicted as different forms of 'noise'. It could also be about a mystery or adventure that Kathleen embarks on that is somehow related to this concept of 'noise'.