I'm not sure specifically as there could be many novels with that title or a similar phrase. It might be about a boy who is running away from something, perhaps danger or his past. It could also be a more metaphorical 'run' like running towards a goal or a new life.
Well, without more context, it's difficult to say precisely. However, if we assume it's a fictional work, it might revolve around a young boy's journey of self - discovery while he is running. This running could be literal, like running through forests and towns, or it could be a symbol for his inner struggle and growth. The novel could also explore themes like friendship, as he might meet different people during his run who help him or hinder him on his path.