There could also be a detective - like character who is running for his life while trying to solve a mystery. He might be getting too close to the truth in a case involving powerful and dangerous people, and now he has to use his wits not only to solve the mystery but also to stay alive while being chased by the bad guys.
There are many possibilities for the main characters. It could be a detective who is on the run because he has uncovered a conspiracy within his own department. Or it could be a family that has to flee their home due to some external threat, like an invading army. Without more information about the story, it's hard to say exactly who the main characters are.
I'm not sure without reading the story specifically, but it could be someone escaping from danger, like a fugitive or a refugee.
The main theme might be survival. In many novels with such a title, the characters often face life - threatening situations and have to run or fight to stay alive.
If it's the story of Lot's wife running from Sodom and Gomorrah, the main characters are Lot, his wife, and the angels sent by God.
Since I haven't read it, I can't say for sure. But it could be a young man and a young woman who are the main characters, as is often the case in love - themed novels.
It's possible that the main characters are outsiders in a society. They might be running because they are different and not accepted. Through their running, they could find others like them and form a new community. Or perhaps they are rebels fighting against an unjust system and their running is part of their resistance strategy.
There's Caballo Blanco. He is a key figure in the running community depicted in the novel. He has a certain charisma and knowledge about running that attracts others.
There's no way to determine the main characters without more information about the 'cut and run novel'. However, in a general sense for this type of story, it might be a character who is fearless and quick - witted. This person could be leading others in the 'cut and run' scenario. Or perhaps it's a young protagonist who is forced to grow up fast due to the need to cut and run. There could also be an antagonist who is chasing the characters who are trying to escape.
Well, the girl herself is surely one of the main characters. But without reading the novel, it's hard to say exactly who else. There might be someone she is running from, like a villainous figure.
It's possible that there are a group of friends or family members as main characters. Their interactions and how they support or hinder each other's enjoyment of life could be central to the story.