A really interesting plot could be a Spiderman fanfic set in an alternate universe where Peter Parker never got bitten by the radioactive spider, but his sister did. She then becomes the new Spiderman, or should I say Spider - Woman, and has to navigate the challenges of being a superhero while also dealing with family expectations. This could explore themes of gender roles in superhero stories.
One idea could be a story where Spiderman has to team up with his greatest enemies to fight a new, more powerful threat from outer space. This would force him to put aside his differences and find common ground with the likes of Doctor Octopus and Green Goblin.
One plot idea could be that Spiderman and Mantis team up to fight a new villain in the city. Mantis uses her empathic abilities to sense the villain's motives, while Spiderman uses his webs and strength to physically combat the foe. Another could be a story where they get accidentally transported to an alternate dimension and have to work together to find their way back home. They might face strange new enemies and allies in this dimension.
Another plot could involve a mad scientist who creates a device that can drain the powers of superheroes. He first targets Superman, but Spiderman gets involved when he sees the chaos in Metropolis. As they try to stop the scientist, they discover that the device has a side effect of giving the heroes new, unexpected powers for a short time. They have to quickly learn to control these new powers while also dealing with the main threat.
One plot idea could be that Spiderman and Silk team up to face a new super - villain who has the ability to manipulate time. They have to use their combined skills and their unique spider - sense in different ways to outwit the villain. Another could be a story where they explore their relationship more deeply while on a mission in an alternate dimension.
One idea could be that Spiderman discovers Rachnera in a part of the city that's been affected by some strange scientific experiment gone wrong. He initially mistakes her for a villain but soon realizes she's just trying to find her way in this new world. They could team up to fight against the real bad guys who are behind the experiment.
One idea could be that Peter Parker gets magically transported to the wizarding world. He could use his Spidey - sense to detect dark magic or danger in Hogwarts. Maybe he teams up with Harry Potter to stop a new villain who is using both magic and advanced technology to cause chaos.
One idea could be that She - Venom has a unique connection to Spider - Man's spider - sense. Maybe her symbiotic abilities interfere with it in unexpected ways, leading to some comical or dangerous situations as Spider - Man tries to adapt. Another could be a story where She - Venom and Spider - Man have to team up to stop a new super - villain who is immune to the regular attacks of both of them, forcing them to combine their powers in creative ways.
One idea could be that the Totally Spies girls are on a mission in New York and accidentally cross paths with Spiderman. They initially mistake him for a villain but soon realize he's on their side. They then team up to take down a common enemy who is using both high - tech gadgets and super - powered minions.
A great plot could involve Spiderman getting injured in a fight and Gwen having to take on his responsibilities for a while. She could struggle with the pressure but also gain a new respect for what Spiderman does. Or perhaps there's a plot where an old enemy of Spiderman returns and targets Gwen to get to him. This would lead to some intense rescue scenes and a strengthening of their bond. Also, a story where they find an ancient artifact that has powers related to their spider - abilities and they have to figure out how to use it without it falling into the wrong hands.
One idea could be that the chubby Spiderman has a hard time swinging between buildings due to his extra weight, so he has to come up with new ways to move around the city. Maybe he invents some sort of web - enhanced jetpack. Another plot could involve him being bullied because of his appearance, but then he uses his intelligence and superpowers to prove his worth. For example, he could solve a big scientific mystery that even the smartest minds in the city couldn't crack.
One idea could be that Spiderman gets caught in the middle of a conflict between the X - Men and one of their powerful enemies. Maybe Magneto is causing chaos in New York and Spiderman tries to stop him on his own at first, but then realizes he needs the X - Men's help. The X - Men, in turn, are initially skeptical of Spiderman but come to respect his skills.