Well, without having read the 'denying the alpha novel' it's hard to say precisely. It could be that the plot revolves around someone denying the power or dominance of an alpha - like a person in a leadership position. Maybe in a dystopian or fantasy setting where there are alpha - like entities ruling, and the protagonist decides to stand against them.
The 'denying the alpha novel' could cover a variety of themes. It might be centered around the concept of rejecting traditional alpha - male or alpha - female archetypes. For example, if it's a romance novel, it could be about a female character who refuses to be submissive to the typical male 'alpha' character and instead forges her own path. It could also be set in a pack - like structure, such as a werewolf story, where the idea of denying the alpha has significant consequences for the social order of the group.