Well, Narcissa Black (her sister) would surely interact with Bellatrix. They could be shown having sisterly moments, but also Bellatrix influencing Narcissa towards darker ways. And then there's Sirius Black. Even though they are on opposite sides, there could be some tense family - related interactions at Hogwarts. Maybe Sirius tries to convince Bellatrix to turn away from the dark side, but she refuses and they have a big argument in one of the Hogwarts corridors.
In this fanfiction, Dudley would surely interact with the Hogwarts professors. Professors like McGonagall would be strict with him, making sure he follows the rules. He might also cross paths with Draco Malfoy. Given Malfoy's attitude towards Muggle - borns, there could be some conflict there. And let's not forget the other students in his house. They would play a big role in his Hogwarts experience, either befriending or ostracizing him.
Voldemort would be a likely character to interact with Harry. Since Bellatrix was one of Voldemort's most loyal followers, he might take an interest in Harry as her son. He could either see Harry as a potential powerful ally or a threat depending on how his powers develop. Another character could be Draco Malfoy. Given the connection between the Malfoy family and the Death Eaters, Draco might have a complex relationship with Harry, perhaps initially seeing him as an equal in the dark magic world but later having doubts as Harry shows signs of not fully embracing the dark side.
Luna Lovegood might be an unexpected character to interact with Regulus. Given her unique perspective on magic and the wizarding world, she could offer him a different view on life after his resurrection. Also, Kreacher, the house - elf who was loyal to the Black family, would surely be involved in his story, as he was very attached to Regulus.
Hermione is the central character as the heir. Harry and Ron will surely be there, supporting her or getting into some trouble with her. Professors like McGonagall could be involved as well. They might either guide Hermione in her new role or be a bit skeptical at first. There could also be some antagonists, like Malfoy, who might try to undermine Hermione's position as the heir.
Obviously, Harry Potter himself would be the main character. Hermione and Ron would also be important as they are Harry's closest friends and would be involved in his journey as the heir.
Severus Snape could also be a character often paired with Bellatrix. They were both on Voldemort's side, but Snape had his own hidden motives. Fanfiction might explore a relationship between them, perhaps a power struggle or a secret alliance that also involves Bellatrix's relationship with Harry in some way.
Definitely Naruto and the Punisher first. Naruto would be intrigued by the Punisher's methods and would try to understand his motives. It's also possible that Sakura could interact with the Punisher. She's a strong - willed character, and she might try to either stop the Punisher if she thinks his actions are too extreme or help him if she sees the good in his goals. And Jiraiya might also be a character who could cross paths with the Punisher. Jiraiya's worldliness and his own sense of right and wrong could lead to some deep discussions between them.
Some Slytherins might oppose her. They are often traditionalists and may not like her new - fangled ideas for the school. For example, Draco Malfoy could be one of the opponents as he has had a long - standing rivalry with Hermione.
The teachers of the major subjects are bound to be present. Snape, as the Potions master, would be there. His presence would add an air of mystery and his sharp intellect would be useful in any discussions. Flitwick, the Charms teacher, would also be important. He could offer his insights on how to make the students' learning experience more magical and engaging through charms.
Ron would be there too. He could be in charge of things like the Gryffindor common room or helping Harry with student relations. And of course, Dumbledore might still have some influence in the background, even if Harry is in control. His wisdom could be a guiding force for Harry as he navigates running the school.