It could make Naruto closer to characters like Shikamaru. Since he's tired of Sakura, he might start spending more time with those who understand him better, like Shikamaru who is smart and can offer different perspectives. With Sasuke, it might create an even more complex dynamic. Naruto might be less likely to try and bring Sakura and Sasuke together if he's tired of her.
Well, Naruto being tired of Sakura could cause some rifts in his relationships with the other Konoha 11. Some might side with Sakura, thinking Naruto is being unfair. Others, like Hinata, might be more understanding of Naruto's feelings. This could lead to a shift in the group dynamics. Also, it might affect Naruto's relationship with Kakashi. Kakashi might try to mediate, but Naruto could be stubborn about his feelings towards Sakura.
If Naruto is tired of Sakura in the fanfic, it could have a big impact on his relationship with the villagers. If Sakura is seen as a 'nice girl' by most of the village, and Naruto is distancing himself from her, some villagers might start to question Naruto's character. On the other hand, those who know Naruto well, like Iruka, might support him. It could also change how Naruto interacts with the other female characters in the village. He might start to avoid female relationships altogether for a while if his experience with Sakura has been so negative.
Well, their argument could make Sasuke more distant. Sasuke already has his own issues and if Naruto and Sakura are arguing, it might seem like chaos to him. He might withdraw further, thinking that his friends can't even get along. For Kakashi, it could be a headache. He has to deal with his team's internal conflicts, and an argument between Naruto and Sakura would mean he has to step in and try to resolve it, which could be time - consuming and affect his other duties.
For the new generation of ninja like Boruto and his friends, they might view Sakura's overprotectiveness as strange. Boruto in particular, who has his own views on Naruto, might not understand why Sakura is so over the top in protecting Naruto. This could lead to some misunderstandings between the generations.
If Naruto gets hurt by Sakura, their relationship could become strained. Naruto might be confused and hurt, both physically and emotionally. He might start to avoid Sakura at first.
It might also affect how their friends view their relationship. If Naruto snaps at Sakura in front of others, their friends might try to mediate or take sides. This could further complicate their relationship as they have to deal with not only their own feelings but also the opinions of their friends.
It could make his relationship with Naruto tense. Naruto might notice Kakashi's special attention to Sakura and feel jealous or confused. After all, Naruto also cares a great deal about Sakura. And with Sasuke, Kakashi's obsession could make Sasuke distrust him more, as Sasuke is also connected to Sakura in his own way.
It can strain their relationship. Naruto's jealousy might make Sakura feel suffocated. For example, if he's constantly interrupting her time with others. But it could also make Sakura realize Naruto's deep feelings for her. If she understands his jealousy is coming from a place of love, it could bring them closer.
Well, it can make things a bit tense with other female characters. For example, Sakura might notice Hinata's possessiveness and find it a bit off - putting. This could create some friction between them as Sakura might think Hinata is being too clingy towards Naruto.
Their relationship might make Sasuke a bit jealous at first. Since Sasuke has his own complex relationship with both Naruto and Sakura. But eventually, he could come to accept it. For their other friends like Kakashi, he would probably be supportive and give them some relationship advice based on his own experiences. Shikamaru might find it a bit of a nuisance at first, thinking it could disrupt the team dynamics, but then see how happy they are and be okay with it.
Regarding the relationship with other characters, Kakashi's overprotectiveness of Sakura can strain relationships. For example, the other ninja in the village may think Kakashi is playing favorites, which could lead to resentment among some. With their own teammates, it can be a bit of a mess. Naruto might try to understand at first but as time goes on, he may get frustrated that Kakashi seems to be only concerned with Sakura's safety. Sasuke may view it as a sign that Sakura is not as strong as she claims and this could further damage their already complex relationship.
It deepens their bond. Naruto's care shows Sakura that he truly values her. She starts to see him in a new light, not just as the goofy Naruto but as a reliable and caring person. This can lead to a closer friendship or even the start of romantic feelings on Sakura's part.