Perhaps a rogue vampire who has his own agenda. He might be jealous of the red knight's power or status and constantly tries to undermine them. This vampire could be very cunning and not afraid to use dirty tricks to get what he wants.
It could be Kaname. Even though he has complex relationships with Zero and Yuki, in a story where Zero dies, Kaname might be seen as the main antagonist. He could be responsible for Zero's death, either directly or indirectly, perhaps out of jealousy or a desire to protect Yuki in his own twisted way.
A more action - packed plot could be the red knight leading a rebellion against the vampire hierarchy. They gather other vampires and humans who are tired of the oppression and fight for a new order. Along the way, they discover secrets about the vampire world that could change everything.
Maybe the Akatsuki as a whole. They are a group of powerful and dangerous ninjas. The Black Knight's presence might disrupt their plans to collect all the tailed beasts. They would see him as an obstacle and try to eliminate him. For example, Pain might think the Black Knight is a threat to his vision of peace through pain and send his subordinates to fight him.
It could be a powerful and corrupted Huntsman. He might have once been a colleague of the Silent Knight but was consumed by greed for power. He now uses his skills to create chaos and try to take over the kingdoms, and the Silent Knight has to stop him.
It could be Orochimaru. In the medieval knight setting, he might be a dark sorcerer who wants to use the power of the knights for his own evil purposes. He could be trying to steal the holy relics of the kingdom which are said to grant great power, and Naruto, as a knight or someone with knight - like qualities, has to stop him.
There could be a rival kingdom led by a tyrant king. This king sees Naruto's village as a valuable asset and wants to conquer it. He has a large army of knights and foot soldiers. His knights are well - trained and equipped, and he uses underhanded tactics to try and defeat Naruto and his comrades in battle.
It could be a vampire hunter's daughter. She might be sent to the school undercover to gather information on the vampires there.
In 'Blood Ties Vampire Knight Fanfiction', one can expect to see different interpretations of the characters' personalities. Some fanfictions might focus on the backstories of minor characters, like how a certain vampire came to be part of the night class in the 'Vampire Knight' universe. It gives fans a chance to delve deeper into the lore.
Maybe a new character could be introduced as the main antagonist in the fanfiction. This character could be a powerful knight from another region who has a personal vendetta against Lelouch or the OC. They might have different beliefs about how the world should be ruled and see Lelouch's actions, and by extension the OC knight's support, as a threat to their vision of order.
Maybe a group of dark wizards who are jealous of the power of the dragon knights. They form an alliance to destroy the dragon knights and anyone associated with them, making Harry and his newfound friends their main targets.