Voldemort could also be an antagonist if there's some sort of crossover between the two universes. He would want Harry back under his control and would see Batman as an obstacle. His dark magic would be a huge threat to Gotham.
Ra's al Ghul could be another antagonist. He might view Harry as an unnatural element in Batman's world and try to eliminate him. Also, he would be interested in the power of Harry's magic and might try to steal it for his own immortality - seeking goals.
The Joker could be a main antagonist. He would be fascinated by Harry's magic and would try to use it for his own evil purposes or just to cause chaos. He might try to drive a wedge between Harry and Batman by using mind games.
Voldemort or his followers could still be antagonists. They might not like the idea of Harry being under Euryale's protection as it could make him more powerful. Another possibility could be some creatures from Euryale's world who are against her taking in an outsider like Harry.
It could be some jealous rivals of Arcuid. They might see Harry as an outsider and a threat, especially if they think Arcuid is giving Harry special treatment or powers. Maybe there are those who want to use Harry against Arcuid for their own gain.
One of the main antagonists could be the Penguin. He is a classic Batman villain and his criminal activities in Gotham would put him at odds with Batman and Nico. Additionally, if Nico's presence in Gotham attracts unwanted attention from the underworld of his own world, perhaps a powerful demigod or a group of magical creatures could also become antagonists. They might not understand or respect Batman's territory and would try to cause chaos. Another possibility is Ra's al Ghul. His long - term plans for Gotham and his extreme views would surely clash with what Batman and Nico are trying to achieve.
One possible main antagonist could be Voldemort still. Even though Harry is now under Sparda's protection, Voldemort would see Harry as a threat and would try to get rid of him. Another could be some of the demons from Sparda's world who see Harry as an intruder or a threat to their plans in the new world order that Sparda is trying to create with Harry by his side.
Definitely Voldemort. He's the main baddie in the Harry Potter series. But in this fanfiction, there could be other villains too. Maybe some jealous Disney characters who don't like Harry getting all of Mickey's attention. Or some dark forces from the edges of both the wizarding and Disney worlds that team up with Voldemort to stop Harry and Mickey's new family dynamic.
It could be another magical creature or group that is jealous of the power that the vixen holds and by extension, Harry as her adopted son. Maybe there is a group of dark wizards who want to harness the vixen's magic through Harry, and they become the antagonists as they try to capture him.
The shinobi council could be antagonists. They would be very suspicious of Naruto being adopted by Jenova, fearing that he will bring destruction to the village. They might try to isolate or even eliminate Naruto.
The Penguin could be a main antagonist. He might see the daughter as a new threat to his criminal operations in Gotham. Since she has the combined skills of Batman and Catwoman, she could easily disrupt his illegal business, like his smuggling operations.
The Ministry of Magic could be the antagonists. Since Harry is in a gang, they might see him as a threat to the order of the wizarding world. They could send Aurors after him and his gang mates, trying to arrest them and break up the gang.
One possible plot could be that Harry, who might be from the Harry Potter universe, is suddenly adopted by Batman in a crossover world. Batman could see Harry's potential and take him under his wing. Harry would then be trained in Batman's ways, learning combat and detective skills. He might also use his own magic in a new way to help Batman fight crime in Gotham, like using magic to disarm villains or solve mysteries that normal means can't.