In a fanfiction, Sirius' reaction to catching Drarry could be complex. He has a deep bond with Harry, so his first instinct would be to protect Harry. If he caught them, he'd want to know what was going on. He might interrogate them separately. He could be especially tough on Draco, given his family's history. But if the story has developed Draco's character in a positive way, Sirius could eventually come around and see that their relationship might not be as bad as he initially thought. It all depends on the specific plot and character development in the fanfiction.
Sirius might react with a mix of surprise and protectiveness. He would be like an older brother or father figure. He'd make sure they were safe and not doing anything too risky.
If Drarry got caught by Sirius, it would be a very tense situation. Sirius has his own set of values and beliefs, and seeing Harry with Draco would probably challenge those. He may initially react impulsively, perhaps even casting a spell to keep Draco at bay while he questions Harry. However, as he realizes that there's more to their relationship than he first thought, he could start to see Draco in a different light. This could lead to a series of events where Sirius becomes a mediator of sorts between Draco and the rest of the wizarding world that still harbors mistrust towards the Malfoys.
Ginny might be extremely embarrassed. She would probably blush deeply and try to hide behind Harry at first.
Some of them would be in awe. For instance, Hawkeye would be amazed by Supergirl's powers. He might even joke about how his arrows seem useless compared to her abilities. Hulk might initially be aggressive, but if Supergirl showed she wasn't a threat, he could become curious. Iron Man would probably want to study her powers, maybe even try to incorporate some of her technology into his suit if possible.
Sirius would probably be very worried and immediately try to help Harry. He might use some basic healing spells he knows.
He'd probably be furious at first. He has a strong sense of loyalty and would feel deeply hurt by Ginny's betrayal.
Harry would likely be quite curious. He'd want to know what these fanfictions were about. Maybe he'd be a bit cautious at the same time, worried that some of the fanfictions might distort Sirius's true character. But overall, I think he'd be intrigued and might even try to find a way to read some of them, just to see what the fuss was all about.
Sirius would be deeply affected. He'd see Harry as a sort of surrogate family, and seeing Harry in such a state would make him feel like he failed in protecting him. He'd do everything he could to make Harry feel better, from getting him medical help to just sitting and talking with him for hours about what's wrong.
Ginny would be very empathetic. She'd probably try to understand Hermione's situation from a female perspective. Ginny might try to get some female friends or relatives to help out, like bringing food or warm clothes to Hermione. Luna would be her usual unique self. She might think that Hermione is on a special spiritual journey and would offer her some very strange but oddly comforting advice.
Sasuke would be very conflicted. On one hand, he has his own goals, but on the other, Naruto is his friend. He might initially try to fight Naruto to stop him from doing harm, but then he would focus on finding a way to break the brainwashing.