There's also the possibility that it was an accident. Perhaps a magical experiment gone wrong in the Hogwarts castle. Harry could have been investigating something strange in the middle of the night and been caught in a magical backlash that led to his death.
It could be a case of betrayal from within. Maybe someone who was thought to be an ally, like a wizard who was secretly working for the dark side all along. They could have used a powerful and unknown curse to kill Harry in the middle of the night without anyone suspecting them at first.
It could be Malfoy. He often has a vendetta against Harry and might have found a way to make him collapse during potions class, either by tampering with his ingredients or distracting him in a way that leads to a mistake in the potion - making process.
One possible plot could be that it causes chaos in the wizarding world. His friends like Hermione and Ron are devastated. They might start an investigation to find out the cause of his death, suspecting dark magic or a hidden enemy. This could lead to a series of adventures as they search for the truth.
It could be Death Eaters. They are always on the hunt for Harry and his friends. If they manage to find Shell Cottage, they might see Hermione as a major threat and use a deadly spell on her.
An unexpected character could be responsible. Maybe a character that Harry thought was harmless but was secretly envious of him. This character could have used some form of emotional manipulation, constantly undermining Harry's confidence and self - worth until his heart was broken and he died.
It could be a fan who wants to explore a darker side of the Ben 10 story. Maybe someone who is interested in how the characters would react in a really tragic situation.
A fan who has a strong emotional connection to the character Ben or the story he belongs to might write a 'ben dies fanfic'. It could be someone who wants to explore different plotlines that involve his death, perhaps to add more depth to the overall story. Maybe a writer who is interested in exploring darker themes and using Ben's death as a catalyst for character development in other characters.
The villagers themselves could be responsible. Their constant ostracization and negative treatment of Naruto could lead to his downfall. He might be pushed to a point where he takes risks that ultimately cost him his life.
Maybe it's a result of a dangerous magical experiment gone wrong. Harry might be trying to test a new spell or a new form of magic that he read about in some old, mysterious book. But he doesn't fully understand it, and it backfires on him, leaving him badly injured.
It could be Death Eaters. They might have finally found a way to capture Harry without alerting Dumbledore. His 16th birthday could be the perfect opportunity as everyone might be a bit more relaxed thinking he's not quite of age yet for the full - on final battle.
There's also a possibility that it was an accident. Maybe Harry was exploring some ancient and dangerous magic, and something went wrong. A spell backfired and instead of achieving what he intended, it put a strain on his heart and led to the heart attack.