It could be a time - traveler. She comes from a future where the world is in chaos and decides to go back in time to change things. However, her plans go awry and she ends up taking over the world instead, believing she can do a better job of ruling it.
A young prodigy who has been underestimated all his life. Fed up with being pushed around, he uses his intelligence and unique abilities to rise to power and become the world overlord.
Maybe a magical creature like a dragon in human form. He has lived among humans secretly for centuries, observing their ways. Tired of their constant wars and destruction, he reveals himself and uses his magic and strength to impose order on the world, becoming the new world overlord.
It could be a young and ambitious wizard who has come to the town to assert his magical dominance.
It could be an ordinary person from our world, like a high school student. They're suddenly thrust into this new world and have to adapt. Their inexperience in this new environment can lead to many humorous and exciting situations.
It could be about a regular person who suddenly gains extraordinary powers and decides to take over the world. Maybe they start by gathering a group of loyal followers and use their powers to outwit existing governments and powerful organizations.
I think Spider - Man would make an interesting main character. He's young and has a different perspective compared to the more experienced Avengers. His journey of growing up and becoming a more integral part of the team could be a central theme in the fanfiction. He also has his own set of personal problems like school and his relationships which could add depth to the story.
Perhaps a minor character from the original Fate series could be promoted to the main character. For example, a bystander in one of the battles who witnessed something extraordinary and was then drawn into the world of the Holy Grail War in a more central way in the 'a new fate fanfiction'.
One possible main character could be a vampire hunter. This hunter might initially be after the forgotten overlord but then realizes that there are greater threats in the vampire world and teams up with the overlord. Another character could be a witch who has knowledge about the spell that made the overlord forgotten and helps him to break it.
Naruto himself could be the main character. Since he's the protagonist of the original series, it would be natural to have him as the center of the fanfiction. He could be drawn into the new game world and have to use his unique skills and determination to succeed.
The main character would most likely be the new thief. They could be an original character created just for this fanfiction.
Obviously, the demon overlord could be the main antagonist. He might have his own motives like ruling the ninja world or obtaining some powerful jutsu that Naruto and his friends are trying to protect.
The Yonko would definitely be major antagonists. Since Luffy is in the New World, the likes of Kaido or Big Mom would be natural choices. Their vast power and influence would pose a great threat to Luffy and his crew.