There's a possibility that a corrupted version of one of the Edolas Fairy Tail members turns out to be the main antagonist. They could be jealous of Erza's strength or be under the influence of some dark force. This character would then use their knowledge of both worlds to create chaos and try to stop Erza from achieving her goals in Edolas.
It could be one of the powerful Edolas officials who oppose Erza's presence or her mission.
It could involve Erza facing challenges in the Edolas version of Fairy Tail. Maybe she has to deal with different versions of her friends or new magical threats specific to that realm.
A group of rogue dragon slayers who have turned to the dark side could be the main antagonists. They envy Igneel's relationship with Natsu and Fairy Tail. They believe that dragons should rule over humans and plan to use their powers to subjugate the world. Igneel and Fairy Tail must stop them.
Well, aside from the obvious ones like Natsu, Lucy, Gray, and Erza, there could also be some supporting characters from the original Fairy Tail story that become more prominent in this 'Back to Edolas' fanfiction. For example, Happy, Natsu's exceed companion, might play an important role. Maybe Wendy Marvell could also be involved, with her healing and sky - dragon slayer magic. And of course, characters like Makarov, the guild master, might also have a part to play in the events that unfold in Edolas.
It could be a former Fairy Tail member who turned to the gangster life. They know all the guild's secrets and weaknesses, so they can be a very formidable opponent. They might have left the guild because they felt betrayed or didn't get the recognition they thought they deserved.
It could be an ancient dragon that has been awakened from a long slumber. This dragon might have a vendetta against Ignia or the Fairy Tail guild for some past transgression.
A group of rogue mages who oppose the idea of Yukino joining Fairy Tail. They might view Fairy Tail as a threat to their own plans in the magical world. They target Yukino as the 'newcomer' in the guild, thinking that if they can get rid of her, they can weaken Fairy Tail. They use various underhanded tactics like spreading false rumors about Yukino within the guild and attacking her when she is on solo missions.
It could be Natsu. He's hot - headed and might not understand Naruto's ways at first. He could see Naruto as a threat to his position in the Fairy Tail guild and start bullying him to assert his dominance.
It could be Zeref. Since he has a complex relationship with Natsu in the original story, he might manipulate things behind the scenes to make the Fairy Tail guild betray Natsu. Maybe he wants to isolate Natsu for his own evil plans.
Zeref could be a great main antagonist. His long - standing connection to dark magic and his complex relationship with the Fairy Tail characters make him a powerful and menacing figure. He could be the one orchestrating the universal war in an attempt to finally achieve his dark goals.
It could be a dark wizard who is jealous of Romeo and Wendy's emerging powers. This wizard might try to steal their magic or stop them from achieving their full potential.