It could be one of the powerful and corrupt prison guards. They might have their own hidden agendas and see Naruto as a threat to their power or secrets within the Blood Prison. So, they start a scheme to make it seem like Naruto has betrayed everyone.
It could be the warden of the Blood Prison. He might be a corrupt figure who is using the prison for his own gain. He sees Naruto as a threat to his operations and tries to keep him locked up at all costs.
The warden of the Blood Prison could be the main antagonist. He might be a power - hungry and corrupt individual who sees Naruto as a threat to his control over the prison. So, he devises plans to get rid of Naruto, which ultimately lead to Naruto's death.
Might be one of the powerful guards who has a grudge against Naruto for some reason. Maybe he believes Naruto is a threat to the order in the prison and tries to get rid of him secretly.
It could be a corrupt ninja from within the village who wants Naruto out of the way. Maybe someone jealous of Naruto's popularity and power, so they frame him and get him sent to prison. This antagonist would then try to keep Naruto in prison by any means necessary.
In the 'Naruto betrayed blood prison fanfiction', perhaps Naruto is betrayed first by someone he trusts inside the prison. This betrayal makes him take actions that are misinterpreted as him turning on the prison. It might also be that a new, powerful inmate arrives and manages to turn the situation around so that Naruto looks like the bad guy. He could be forced to fight against the prison guards to protect himself or others, which would be seen as betrayal.
It might be a rogue ninja from the Wave. They could have a vendetta against Konoha and see Naruto as an easy target to frame and cause chaos between the two places.
Obviously, Kami would be the main antagonist. Since the title says 'naruto betrayed by kami', Kami is the one doing the betraying, which makes him the bad guy in this fanfiction.
Another possibility is that there is a false god or a demon that has influenced the true gods to betray Naruto. This false entity could be the real mastermind behind the whole situation. It wants to use Naruto's downfall to gain more power or to bring chaos to the ninja world. So Naruto not only has to deal with the betrayed by the gods part but also has to uncover the true source of this conspiracy which is this false god or demon.
It could be Xehanort. He's a powerful and devious character in Kingdom Hearts. If he sensed Naruto's power and saw him as a threat, he might engineer a situation where Naruto is made to feel betrayed. Xehanort could manipulate the events and the people around Naruto to make it seem like his new friends in the Kingdom Hearts world are against him, all so that he can either eliminate Naruto or turn him to his side.
It could be a new character, someone who is jealous of Naruto's growing power and popularity among the girls. This person might spread false information to turn everyone against Naruto. Maybe a rogue ninja who has infiltrated the village and has a vendetta against Naruto for some unknown reason.