A new villain created specifically for this fanfic could be an ex - S.H.I.E.L.D. agent gone bad. This agent has access to a lot of top - secret technology and has a vendetta against both superheroes and spies. He wants to create a new world order where he is in control, and he sees Spiderman and the Totally Spies as the main obstacles to his plans.
The Green Goblin could also be a great antagonist. He could be interested in the Totally Spies' technology and try to steal it. His glider and pumpkin bombs would be a big threat to both Spiderman and the spies. He might also try to frame Spiderman for his own crimes to keep the heroes distracted.
It could be Doctor Octopus. He might team up with some evil spy organization. His mechanical arms and scientific knowledge combined with the sneaky tactics of the spies would make for a formidable foe for Spiderman and the Totally Spies.
Dr. Octopus could be a great main antagonist. He could team up with a female super - villain from the Totally Spies universe. Together, they could create a plan to steal some top - secret technology. Dr. Octopus uses his mechanical arms to cause chaos in the city, while the female villain uses her own unique powers to keep the Totally Spies and Spider - Man at bay.
One idea could be that the Totally Spies girls are on a mission in New York and accidentally cross paths with Spiderman. They initially mistake him for a villain but soon realize he's on their side. They then team up to take down a common enemy who is using both high - tech gadgets and super - powered minions.
One idea for a Spiderman and Totally Spies crossover fanfic could be that the Totally Spies are on a mission in New York. They accidentally stumble upon one of Spiderman's battles with a villain. Spiderman is initially suspicious of them but soon realizes they have the same goal of protecting the city. They then team up, with the Totally Spies using their high - tech gadgets and Spiderman his superpowers to take down the bad guys.
A possible plot could be that there is a threat to the world that involves both superpowers and high - tech espionage. The Totally Spies are called in to investigate the technological aspect, while Spiderman is already on the scene dealing with the super - powered part of the threat. They cross paths and at first are not sure if they can trust each other. But as the situation worsens, they realize they need to work together. They combine their unique skills, like Spiderman's web - slinging and the Totally Spies' ability to blend in and use advanced gadgets. In the end, they defeat the common enemy.
It could be the Joker. Imagine the Joker getting involved in a global scheme and teaming up with some international bad guys. His chaotic nature would be a huge challenge for both Batman and the Totally Spies. He would use his usual tricks like laughing gas and mind games, but on a much larger scale.
Green Goblin could also work well. He could be jealous of all the attention Spiderman is getting at the homecoming and decides to crash the party. His maniacal nature would contrast well with Deadpool's zany humor and Spiderman's more responsible heroism.
A combination of Green Goblin and a chaos - causing creature from Equestria. The Green Goblin could team up with this creature and use his glider and bombs along with the creature's ability to spread chaos. They would target both Spider - Man's city and Twilight Sparkle's home, causing destruction and trying to assert their control.
Sam, Clover, and Alex are the stars of Totally Spies. Sam has a great sense of logic and is good at analyzing situations. Clover brings the style and charm to the team, and she's not afraid to use her looks to her advantage during missions. Alex, on the other hand, is always ready for action and her enthusiasm often gives the team an extra boost.
The Kingpin could be a great antagonist. He could be trying to take over more of the city and sees Spiderman and Tigra as threats to his plans. He uses his criminal network and his physical strength to try and stop them.
A new character could be created specifically for this fanfic. A mad scientist who is obsessed with cross - species experiments. He sees Rachnera as a perfect specimen and wants to use her to create an army of hybrid creatures. He would target both Rachnera and Spiderman as they try to stop his evil plans.