Well, Sasuke could be one of the main characters involved. Since he has a complex relationship with Naruto, he might play a role in the betrayal, either as a part of the group that betrays Naruto or as someone who is conflicted about the situation. Sakura could also be involved. She has her own opinions and relationships within the Naruto universe, and she may be part of the group that turns against Naruto for some reason.
Sasuke is often involved. Since Naruto and Sasuke have such a complex relationship, in this 'beyond godlike' scenario, Sasuke might be either a rival trying to match Naruto's new powers or an ally helping him control or use them. Another common character is Kakashi. He could be Naruto's mentor in understanding and managing these extreme powers.
Sasuke could be involved. He and Naruto often have intertwined stories. Sasuke might either be an ally in Naruto's destruction of Iwa, or he could be there for his own reasons, like seeking power or revenge.
Sasuke is often involved. Since he and Naruto have a complex relationship, his reaction to Naruto's demon form can be a major plot point. He might be initially suspicious or even see it as a new way to compete with Naruto. Sakura could also be there. She might be worried about Naruto and try to find a way to help him control this new form.
Sasuke could be one of the main characters. At first, he might be among those who doubted Naruto, but as Naruto starts to prove everyone wrong, Sasuke has to re - evaluate his views. This could lead to some interesting character development for Sasuke as he sees Naruto's growth and realizes his own misjudgment.
Sasuke could be involved. He might either try to stop Naruto from leaving, believing that they should face whatever comes together in Konoha, or he could decide to join Naruto on his journey, as they have a deep bond.
He might initially be in shock. Naruto, being the strong - willed character he is, would probably first try to understand why everyone has turned against him. He could start by seeking answers from those closest to him before he decides on his next course of action, like whether to fight back or try to win them back.
Tsunade for sure. As the Hokage and also a medical expert, she would be furious about Naruto escaping the hospital. She might send some ninjas to bring him back.
There might be characters from Iwa who oppose Naruto. For example, the Tsuchikage of Iwa would surely be involved as the leader of the village Naruto is attacking.
It could be the very villagers who once looked up to Naruto. Their betrayal could turn them into antagonists as they might try to further harm Naruto to protect their own interests.
Well, characters like Jiraiya could be really interesting in a 'naruto crossover godlike fanfic'. He has a lot of knowledge about the ninja world and different powers, so his encounter with god - like beings would be full of potential for interesting stories. Tsunade too, as a powerful Hokage, could be involved. She could represent the Naruto world's power structure when dealing with these otherworldly god - like entities. And then there's Orochimaru, who is always seeking more power, so he would be very likely to get involved in any situation where there are god - like powers to be had.