One idea could be that as a female Naruto, she might face different challenges in the ninja academy. For example, the boys might underestimate her at first. Minato could train her in unique ways, like focusing more on stealth and agility which are often associated with female ninjas in some stories. This could lead to her developing her own signature jutsu that combines her natural strength and her newfound skills.
Another plot idea is that she discovers secrets about her mother that Minato has been hiding from her. This could drive her to explore her own identity more deeply. And as she grows, she might face opposition from some in the village who don't believe a female can be as strong as a male. But through her determination and Minato's guidance, she overcomes these obstacles and becomes a respected and powerful ninja.