It could be written from the perspective of how the other characters react. Hermione would likely be very scientific about it, trying to find a way to reverse it while also being supportive. Ron might be a bit more shocked and clumsy in his support. And Dumbledore could be the wise figure, guiding Harry through this strange time, perhaps having some hidden knowledge about such a phenomenon from the past of Hogwarts.
Another approach could be to make it a part of a new prophecy. The prophecy could be related to a new threat to the wizarding world that can only be averted if Harry goes through this pregnancy. It could be something that ties into the balance of magic in the world, and Harry's unborn child could hold the key to saving the wizarding world from a great danger.
Another possibility is a crossover with a more magical or otherworldly franchise. For example, if there's a crossover with a series that has powerful deities or entities, one of them could be responsible for Optimus' pregnancy. The story would then revolve around the interactions between the two different universes and how Optimus copes with this new state.
You could write it from the perspective of the hunters. Maybe it was an accident during a training exercise gone wrong. The hunters could then be filled with remorse and guilt, especially those who were directly involved. Their internal struggle and journey to make amends could be a major part of the fanfiction.
One way could be to focus on the emotional journey. Hiccup and Astrid might initially be shocked but then gradually grow excited about the new life. They could start making plans for their future as a family, like building a new home suitable for a baby. They might also face challenges from their community, but their love for each other helps them overcome.
One possible plot could be that Harry and Fleur's pregnancy is a result of a magical accident during a joint mission. They initially struggle with the news, as they have different worlds and cultures. Harry is from the wizarding world of Britain and Fleur is from France. But as the pregnancy progresses, they start to discover new things about each other and their respective heritages, and they come together to prepare for the arrival of their child. They might face opposition from some quarters who think their union is strange, but they overcome all odds with their love for each other and the future of their family.
One way to write it uniquely is to focus on the magical or supernatural aspects of Stevonnie's pregnancy. Since they are a fusion, there could be some extraordinary things that happen during the pregnancy that are related to their gem powers. For example, the baby could have some sort of gem - related ability even before birth.
One creative way is to have a soldier from a parallel magical world come to the 'Harry Potter' universe. This soldier could bring new spells or combat techniques that Harry and his friends have never seen before. It would add an element of mystery and newness to the story.
One creative way is to have a time - travel plot. A character travels back in time to learn about a long - lost surgical technique from the founders of Hogwarts era. For example, Salazar Slytherin might have known a dark - magic - influenced surgery that could be adapted for good. Another way is to introduce a new magical disease that requires a blend of Muggle and wizarding surgical knowledge. So, a character like Luna could bridge the two worlds in finding a cure.
An alpha lord could be incorporated as a time - traveler. He comes from an era long before Harry Potter's time and has knowledge of forgotten spells and magic. He could use this knowledge to change the course of events in the current wizarding world, for example, preventing certain dark events from happening or enhancing the power of the good side.
It should start with a deep understanding of what makes each franchise special. For Harry Potter, it's the magic system, the houses at Hogwarts, and the battle against Voldemort. For One Piece, it's the Grand Line, the Devil Fruits, and the search for the One Piece. In the fanfiction, these elements should be carefully incorporated. Maybe have a story where some of the Hogwarts students are kidnapped and end up in the One Piece world, and the Straw Hat Pirates help them get back home while also learning about magic along the way. This way, both franchises are respected and it creates an exciting new story.
It can focus on the support system they build. For example, showing how their friends come together to help them with baby stuff or just be there for emotional support.