Perhaps a powerful wizard or sorcerer who has some vendetta against Percy's family. This antagonist could have used dark magic to harm Percy's loved ones, which would drive Percy to seek revenge. The wizard would be a formidable foe, with great magical powers that Percy would have to outwit and overcome.
It could be an old rival from Percy's past, someone who has always been jealous of Percy's abilities and has finally found a way to cause him great harm. This person would be a perfect antagonist as Percy would have a strong motivation to get revenge on them.
A corrupt politician or leader in Percy's world could also be the antagonist. If this person has wronged Percy or his community, Percy might decide to take revenge. This could involve exposing the politician's corruption and bringing them to justice, which would be a form of revenge while also serving the greater good.
Percy could be a young boy who has just moved to a new neighborhood. He's shy and misses his old friends. So, when he meets a friendly neighbor, he wants to cuddle as a way of showing his need for friendship and comfort.
It could be someone from Naruto's past who has wronged him deeply. Maybe a hidden enemy from his childhood or a ninja who has a long - held grudge against his family. For example, a rogue ninja who was involved in the death of Naruto's parents in a different way than in the original story.
A possible main antagonist could be Eris, the goddess of strife. She might be jealous of Aphrodite's beauty and power and see Percy as a tool to disrupt Aphrodite's plans. Eris could send her minions to create chaos and conflict between Percy and Aphrodite, trying to make them turn against each other.
It could be an old enemy from their past, like a resurrected Titan or Giant. These powerful foes might manipulate Percy and Jason into betraying their friends as part of a grand plan to regain power or take revenge on the demigods.
It could be a rogue ninja who has a vendetta against Naruto and sees Hinata as a way to get to him. This antagonist might try to disrupt the relationship between Naruto and Hinata where Hinata wants Naruto to be dominant, for example by spreading false rumors about Naruto's methods of training Hinata.
Perhaps an ancient sea god who has a grudge against Thetis. This god sees Percy as a way to get revenge on her. He could send all kinds of sea - based disasters and creatures to attack Percy and his friends. He might also try to corrupt Percy and turn him against his own values.
A group of dark forces or minor gods could be the antagonists. They might believe that the union of Percy and Artemis would disrupt the balance in a way that benefits them. So, they engineer the situation where Percy is forced to marry Artemis, hoping to use the resulting chaos to their advantage. They would likely try to keep Percy and Artemis from finding a way out of the forced marriage.
Maybe an old and powerful monster that has long been trapped in Tartarus could be the main antagonist. It sees Percy as a threat or a source of entertainment, and it tries to stop him from finding a way out or from getting stronger.
It could be an old enemy of the gods, like Kronos. Even though he was defeated before, he could find a way to come back and target Percy and Apollo specifically. Since Percy has been a thorn in the side of many of the Titans' plans before, and Apollo is a powerful god, Kronos might see them as a threat to his new - found or potential power.
It could be an ancient and powerful god who has long been plotting against Percy. This god might be jealous of Percy's power and popularity, so he devises a plan to turn Percy into a killer, knowing that it will lead to Percy's downfall and his own rise in power.