In terms of his relationships with his Slytherin peers, some might look down on him. But others could be intrigued. Pansy Parkinson, for example, might see Draco as a girl as a threat to her status as the 'queen bee' in Slytherin. However, some of the more open - minded Slytherins could befriend Draco and help her deal with the challenges of being a girl in a very traditional and often misogynistic wizarding society.
When it comes to Draco's relationship with Harry Potter and his friends, things could get really interesting. Harry might initially be shocked but could also feel a sense of pity. Hermione could be more sympathetic and might try to help Draco adjust, which could lead to an unlikely friendship. Ron, on the other hand, would probably be the most skeptical and might take a long time to accept this new Draco.
His personality might become more empathetic. As a girl, Draco could start to see things from a different perspective. For example, he might be more sensitive to the way others are treated, especially other girls in Hogwarts.
A possible fanfiction plot could be that Draco, now a girl, discovers new magical abilities that were suppressed in his male form. These powers could be related to a more intuitive connection with magic, something that is often associated with femininity in the wizarding world. This newfound power could put her in a position where she has to choose between using it for the benefit of Slytherin or for the greater good of Hogwarts, creating a moral dilemma for her character.
In terms of her relationships with other Slytherins, the boys in the house might either be overly protective or try to take advantage of her. Some of the Slytherin girls might see her as a threat, especially if she's getting more attention from the boys or from the teachers. But there could also be a group of Slytherin girls who form a strong clique with her. And her relationship with Dumbledore could be one where he tries to encourage her to break free from the more traditional and sometimes dark Slytherin values, seeing her as a potential force for good in the house.
His relationship with Kagome would change significantly. Kagome might see Inuyasha in a new light, perhaps more as a sister - like figure at first, but then as she gets used to the new form, there could be a shift in their romantic undertones. With Miroku, Miroku would be more respectful in a different way. He might be less likely to tease Inuyasha in the same way he did before. Sesshomaru, on the other hand, might initially be disgusted or confused by his half - brother's new form, but it could also lead to some interesting developments in their rivalry as Sesshomaru tries to figure out if this new Inuyasha is still a worthy opponent.
With his Slytherin peers, Draco's relationship would shift. He might encourage them to be more inclusive and less focused on pure - blood supremacy. This could make him an outcast among some of the more traditional Slytherins, but also gain him new allies who are open to change.
If Draco becomes a girl, his relationship with his Slytherin friends would likely change. Some might be more protective of her, while others could be jealous of the attention she gets. His relationship with Harry Potter would also be different. Instead of the typical rivalry, there could be a more complex dynamic, perhaps even a begrudging friendship as they both realize they have more in common than they thought. And with his family, his father might have a hard time accepting the change at first, but his mother could be more understanding and help her navigate this new identity.
In the Hogwarts hierarchy, things would change. Hermione is often seen as a bit of an outcast by some Slytherins because she's a Gryffindor. Draco, now in her body, would face a different kind of discrimination or at least a lot of strange looks from his own housemates. He would also have to deal with Hermione's reputation among the teachers. Some teachers might expect the same level of knowledge and participation from 'Hermione' (who is actually Draco), and he would struggle to meet those expectations.
His relationship with his parents would likely change. His mom might start treating him more like a daughter, perhaps with different rules or expectations. His dad might be a bit more protective. With his friends, the boys might be a bit more shy or awkward around him at first. And the girls might be more accepting and include him in their girl - only activities.
With Hermione, he might see her in a new light. Instead of looking down on her as a Mudblood, he could admire her intelligence. They could work together on a project to improve the education system in the wizarding world. He would learn from her, and they could develop a mutual respect that was absent in their original world.