In this fanfiction, the main characters would include Ash and his Pokemon team. But there could also be new characters introduced. Maybe a mysterious healer or a powerful trainer who has some knowledge about what's causing Ash to collapse. These new characters could either be helpful or create more obstacles for Ash and his friends in their quest to get him back to normal.
Obviously, Ash would be the main character since he's the one collapsing. His Pikachu would most likely be a key character as well. Pikachu is always by Ash's side and would probably be very concerned and try to help when Ash collapses.
His other Pokemon like Bulbasaur, Charmander, and Squirtle could also be important characters. They have a strong bond with Ash and would surely be involved in trying to figure out what happened to him and how to help. Additionally, his friends like Misty and Brock might be in the story. They could be the ones to find Ash when he collapses and then try to get him the help he needs.
The main characters would surely include Ash. In Pokemon Red, the rival character, Gary (or whatever name you choose for the rival in the game), could also play a major role. And of course, the various gym leaders from Pokemon Red. They could have different encounters with Ash, some might be friendly and help him, while others could be more challenging opponents. Also, Professor Oak might be involved, as he is connected to both Ash's world and the world of Pokemon Red in some ways.
The main character is surely Ash. He is the one who is being betrayed. Mew is another important one. It might be that Mew is the cause, directly or indirectly, of Ash's betrayal. Then, Ash's Pokémon partners are likely to be main characters too. They might be confused or forced to side against Ash. And there could be some antagonists in the story, perhaps some evil trainers or organizations who are behind the plot to make Ash look bad and get betrayed.
Obviously, Ash would be one of the main characters, since he's the one turning into Victini. Pikachu would also be important as Ash's most loyal Pokémon. And Victini itself could be a key character, either as a part of Ash now or as an entity that helps Ash understand his new form.
The main characters would surely be Ash and Mewtwo. But there could also be other Pokemon that play important roles. For example, Pikachu might have a different relationship with Ash since Ash was raised by Mewtwo. And perhaps some of Mewtwo's clones could also be involved, adding more depth to the story.
Gary Oak is a likely character. He has always been a rival to Ash and in fanfiction, he might betray Ash out of jealousy or a desire to be the ultimate Pokémon trainer. Another could be Misty. Maybe she gets influenced by some external force or her own insecurities and turns against Ash. Brock could also be a candidate in some stories. If he falls in love with a girl who has a vendetta against Ash, he might be forced to choose between his loyalty to Ash and his new love interest.
Obviously, Ash is going to be the main character. His Pokémon, like Pikachu, Charizard, and all the others he has caught over the years, will also be important characters.
Well, it might be that in this fanfiction, Ash is exploring a new and dangerous area in the Pokemon world. He encounters some strange phenomena or powerful wild Pokemon. There could be a situation where he is poisoned or affected by some negative energy. His body can't handle it and he collapses. His friends or Pokemon then have to search for a cure or a way to revive him, which could be the main focus of the story.
He'll surely meet the Alola region's professors. Also, the local trial captains are very likely to cross paths with Ash. And of course, the regular Pokémon trainers in Alola.
Gary could be a likely character. He has always been Ash's rival and there could be a plot where his jealousy or some other motive leads him to betray Ash. Another could be one of his so - called friends from the Pokemon League who might be influenced by power or some dark secret. Or, in some really dark fanfictions, it could be a Pokemon that Ash trusted deeply but for some reason turns on him.
Since it's an 'ash the pokemon fanfiction', Ash is the central figure. But it could also feature his friends from the original series like Misty and Brock. And of course, the villains he encounters would be important characters too. There may be new characters created by the fanfiction writer, such as a mysterious trainer who has a rare and powerful Pokemon that Ash has to face.