It could be that Sam is an angel who has lost his memory. The main plot then would be his quest to regain it. As he travels around in the Supernatural universe, he starts to have flashbacks and strange encounters. These could be clues to his past identity and his role as an angel. Along the way, he teams up with other hunters who initially are skeptical of him but later realize his importance. And his journey of self - discovery becomes the central theme of the fanfiction.
Dean would most likely be one of his main allies. Dean has always been there for Sam in the Supernatural series, and even if Sam is now an angel, their bond would still be strong. Dean could help Sam navigate his new angelic abilities and protect him from those who might want to harm him because of his new status.
A possible plot could be Sam's relationship with Dean in this new form. Dean might be initially skeptical or even a bit scared of Sam's transformation. Sam could then try to convince Dean that he's still the same person on the inside. Also, Sam could be on a mission given to him by a higher - up angel. But he starts to question the motives of the angelic hierarchy as he realizes some of their actions might not be as noble as they seem. He could then use his new powers to try and change things from the inside.
She could be a nephilim, half - angel and half - human. This would put her in great danger as both angels and demons would be after her. Sam and Dean would have to constantly protect her and figure out a way to keep her powers in check.
In this fanfiction, Max might be on a mission to find other transgenics who have gone missing. Sam and Dean get involved when they notice some strange disappearances in the area that seem to be related to Max's search. Sam uses his psychic abilities (if we consider some AU elements) to sense where the missing transgenics might be. Dean, on the other hand, helps Max break into the facilities where they are held. Along the way, they face various challenges like security guards, booby traps, and even some supernatural elements that are guarding the place.
Well, it depends on the plot. Maybe his brother Dean will go on a revenge spree against whatever injured Sam. He could start hunting down the creature or person with a vengeance.
In fanfiction, if Sam was kidnapped, it could lead to a very intense story. Dean would surely go on a rampage to find him. Maybe Sam was kidnapped by a powerful demon who wants to use him for some dark ritual. It could also be a new, unknown enemy who has a vendetta against the Winchesters.
Well, it's clearly Sam. These fanfictions often center around Sam's transformation into a 'traitor'. It could be due to various reasons like being influenced by dark forces or having a different view on how to deal with the supernatural threats compared to his brother Dean and other allies. The whole story then unfolds around his character and how others react to his betrayal.
One common plot twist could be that the curse is related to a powerful supernatural entity that wants to use Sam's unborn child for some dark purpose. Maybe it's a demon who plans to possess the baby as soon as it's born. Another could be that the pregnancy is a false one, created by the curse to deceive Sam and his friends into believing he's carrying a child, when in fact it's a trap to lure them into a dangerous situation. For example, it could be a spell by a witch to get revenge on Sam for something he did in the past.
He could be poisoned. There are many supernatural creatures in the Supernatural universe that could use poison. For example, a witch could create a poisoned potion and trick Sam into drinking it.
One possibility is that Max's enhanced abilities would intrigue Sam and Dean. They might initially be suspicious of her, but as they learn about her origins and her fight against the corrupt forces in her own world, they could see her as an ally. Max could also offer a different perspective on the supernatural, as she comes from a world of genetic experimentation rather than traditional supernatural elements.