Another concept could be that a character from Lord of the Rings, like Legolas, somehow gets transported to the world of Prototype. There, he would have to adapt to the modern - day setting and deal with the infected. He could use his archery skills and elven agility in a completely different environment. His presence might also cause a stir among the military and scientific communities in the Prototype world, as they try to figure out who he is and where he came from.
A crossover with the Star Wars universe would also be cool. The Jedi could be like the wizards in Middle - earth. Maybe Aragorn could learn some lightsaber skills from the Jedi and use them against the orcs. And the Force could have an interesting interaction with the magic in Middle - earth.
Another interesting concept is that Vlad is a lost hero from a far - off land who arrives in Middle - earth. He could use his skills in combat and his knowledge of dark magic to help the Fellowship. For example, he might be able to use his vampiric speed to quickly scout areas or use his charm abilities to deceive the enemy. He could also have a complex relationship with Aragorn, either as a rival or an unexpected ally.
One idea could be that the Dragonborn from Skyrim somehow ends up in Middle - earth. Maybe they are mistaken for a powerful wizard due to their Thu'um abilities. Another plot could involve the One Ring being found in Skyrim and the different factions vying for its power, just like in Middle - earth. A third interesting plot would be characters from Lord of the Rings traveling to Skyrim and having to deal with the cold, the dragons, and the political unrest there.
One idea could be that the characters from Middle - earth accidentally stumble into Narnia through a magical portal. For example, Aragorn and Legolas could find themselves in the middle of the Narnian forest and team up with the Narnians to fight a common enemy, like an ancient evil that threatens both worlds.
One idea could be that the vampires from Twilight are drawn to the power of the One Ring. They might see it as a source of great power that could enhance their abilities. Another plot could involve a character from Twilight getting transported to Middle - earth and having to adapt to the new world while also dealing with the threat of Sauron. Or perhaps the werewolves from Twilight could form an alliance with the Ents in Middle - earth, as they both have a connection to nature.
One idea could be that Bilbo Baggins discovers a hidden relic during his adventures in 'The Hobbit' that later becomes crucial in the fight against Sauron in 'The Lord of the Rings'.
One idea is that Dracula is drawn to Middle - earth because of the power of the Rings. He believes that he can use their power to enhance his vampiric abilities. He tries to infiltrate the Fellowship to get closer to the One Ring. Another plot could be that Dracula has a history with some of the dark forces in Middle - earth, like the Nazgûl. They were once his allies or enemies in a different time, and this connection affects how he interacts with the events of the Lord of the Rings.
One idea could be that the Jedi and the Fellowship team up. The Jedi's use of the Force could be combined with the magic in Middle - earth. For example, they could fight against a common enemy like Sauron who has somehow gained control over some Sith artifacts, leading to a dark and powerful force in Middle - earth that both groups must combat.
Perhaps the One Ring could have an unexpected reaction to Naruto's chakra. It could either be attracted to it or repelled. This could create an interesting plot where Naruto has to deal with the power of the Ring while also trying to find a way back to his own world.
One idea could be to cross RWBY characters with characters from another popular anime, like Naruto. Imagine Ruby with the ability to use Naruto's shadow clone jutsu. Another could be a crossover with the Harry Potter universe, where the RWBY characters attend Hogwarts and have to deal with magic and dark wizards. Or perhaps a crossover with the DC universe, with RWBY characters teaming up with the Justice League to save Remnant from a greater threat.