Bella might go into a deep depression. She was so in love with Edward, and his death could shatter her world. She could become withdrawn and isolate herself from her friends and family.
Edward would likely be in a state of panic. He loves Bella deeply, so he'd probably do everything in his power to save her. He might search for a cure or a way to reverse whatever is causing her to die.
He could be devastated. Edward is deeply in love with Bella, so he might go into a state of depression. He may isolate himself from his vampire family and friends, constantly replaying in his mind what went wrong in their relationship.
Edward might be initially shocked. He has always seen Bella as his own and this sudden change could be hard for him to accept. He could become withdrawn and moody, similar to how he was before Bella entered his life.
Edward might be initially shocked and heartbroken. He has been in love with Bella for a long time, so her leaving for Jasper would be a huge blow. He could become withdrawn and moody, brooding over what went wrong.
There are other fans who are interested in exploring different storylines. They see it as a creative way to expand the Twilight universe. They might enjoy seeing how the characters would react in such a difficult situation, even if it's not in line with the original story.
She could be heartbroken. After all, she's pregnant and the person she loves has left her. She might feel abandoned and alone, crying a lot and wondering why Edward would do such a thing.
Often, Bella reacts with intense heartbreak. She might isolate herself from her friends and family, feeling like she can't trust anyone anymore after Edward's betrayal.
Bella might initially be terrified. She is a human being kidnapped by a vampire, after all. She could struggle and try to escape, using her wits and any available resources. However, since she has feelings for Edward in the original story, part of her might also be conflicted, wondering if there is a good reason behind his actions.
Well, at first, Edward would be in shock. He wouldn't believe that Bella actually left. Then, he would likely start to search for her frantically. He might go to all the places they used to go together, hoping to find her. His reaction could also be one of self - blame. He would think that it was all his fault, that he didn't protect her well enough or love her the right way. As time passes, he could become more resigned to the situation. But he would never really forget her. He might even try to keep an eye on her from a distance, just to make sure she's okay, even though she left him.
Together, they would likely try to make Renesmee understand that their relationship is special and that her presence is also special. They might give her a hug or some form of affectionate gesture to show that they are a family unit and that her walking in is just a normal part of family life, even if it was an intrusion on their private time.