Perhaps there is a portal that connects Cybertron and Equestria. Some ponies accidentally end up on Cybertron and are shocked by the mechanical world. The Transformers have to help them get back home. Meanwhile, some Autobots are curious about the ponies' world and decide to accompany them. This leads to a cultural exchange of sorts between the two groups, with lots of misunderstandings at first but then growing respect and friendship.
Imagine a powerful artifact that has the ability to control both technology and magic. It falls into the wrong hands, and both the Transformers and the ponies are affected. They must join forces to retrieve it. Rainbow Dash's speed and agility could be useful in navigating the complex landscapes of Cybertron, while Bumblebee's ability to communicate in different ways could help bridge the communication gap between the two species.
One idea could be that the Autobots find themselves in Equestria due to a space - time rift. They team up with the ponies to fight a common enemy like a new breed of Decepticons who are after the magical energy in Equestria. The ponies could use their magic to help the Autobots repair and upgrade, while the Autobots offer their advanced technology to protect Equestria.
One idea could be Discord causing chaos in Equestria that only the Mane 6 can stop with their unique friendship powers. For example, he might mix up the elements of harmony, and the ponies have to go on a quest to put them back in order while dealing with Discord's wacky challenges.
One plot idea could be that the Star Trek crew discovers a planet where Transformers have been in a long - standing war. The Enterprise crew tries to broker peace between the Autobots and Decepticons. Another could be a situation where the technology of the Transformers somehow gets integrated into the Star Trek universe's ships, creating super - powered vessels. Or perhaps a Transformer gets beamed onto the Enterprise and has to adapt to life among the crew while they figure out how to send it back to its own world.
One idea could be that the Jaegers are equipped with Transformer technology. For example, their power cores could be replaced with energon, giving them new abilities. Another plot could involve the Transformers teaming up with the Jaeger pilots to fight a common enemy that threatens both Earth and Cybertron. Maybe a new breed of Kaiju that can also assimilate Transformer technology.
A great plot could be that a powerful artifact from the Transformers universe is found on Earth and it has the power to either save or destroy the planet. The Avengers initially think it's a new weapon or power source, while the Autobots know its true origin. They have to convince the Avengers of its importance and together protect it from the Decepticons and any other villains who want to use it for their own evil purposes.
One idea could be that Harry Potter and his friends accidentally end up in the world of My Little Pony. They could learn about the magic of friendship in Equestria, which is different from the magic they know in the wizarding world. Maybe they help the ponies fight a dark force using their unique spells.
Well, perhaps there could be a crossover where Scooby and Shaggy accidentally eat some magic cupcakes in Equestria that give them the ability to talk to the ponies in a special way. Then they discover that there is a mystery surrounding a disappearing magical element in Equestria. The rest of the Mystery Inc. gang shows up to help, and they all join forces with the ponies like Rainbow Dash and Fluttershy to find out what's going on and save the day.
Maybe the Ghost Rider's powers are somehow connected to an ancient magic in Equestria. He could be on a quest to find out the origin of his powers and in the process, he befriends Rainbow Dash. Rainbow Dash is intrigued by his ability to fly on his flaming motorcycle and they start to explore different parts of Equestria together, all while uncovering secrets about his powers.
One idea could be that Lucifer, with his charm and manipulative skills, gets involved in the power struggles among the Autobots and Decepticons. He might try to use their war for his own amusement or to gain some sort of power. For example, he could offer a deal to Megatron to help him defeat the Autobots in exchange for something valuable in the underworld.
Maybe the Transformers end up in Remnant due to a space - time rift. The Grimm might be attracted to the Energon that the Transformers carry. The RWBY teams would have to team up with the Transformers to fight off both the Grimm and the Decepticons if they also show up. Yang could learn some combat moves from the Autobots, which would add a new dimension to her brawler style.