A plot could involve the male human moving to a small town where there are rumors of a female werewolf. He doesn't believe it at first, but then he has a strange encounter with her. As they interact more, he discovers that she is not as terrifying as the stories make her out to be. They start to rely on each other, and their relationship grows from there. Maybe she protects him from other supernatural threats in the town, and he helps her integrate better with the human side of the town when needed.
One idea could be that the male human stumbles upon the female werewolf in the forest while she is injured. He helps her, and as she heals, a bond forms between them. They have to deal with the werewolf pack's initial mistrust of the human.
A possible plot is that a male human is part of a diplomatic mission to make peace with the yautja race. A female yautja is assigned to be his guide and protector during his stay on their planet. At first, they have a lot of misunderstandings due to their different species' ways. But as time passes, they begin to respect and eventually fall in love with each other through shared experiences like facing a natural disaster on the yautja planet together.
One idea could be that the female werewolf is from a hidden tribe in the Naruto world. Naruto stumbles upon her while on a mission in a forest. She initially sees him as a threat but as they interact more, they find common ground in their sense of loyalty to their respective groups. They could team up to fight a common enemy, like rogue ninjas who are hunting the werewolf tribe for their special abilities.
One idea could be a Pokemon trainer who gets bitten by a werewolf-like Pokemon and starts to take on werewolf - like traits. They then have to struggle with controlling their new powers while still trying to compete in Pokemon battles.
One idea could be that the werewolf girlfriend has to hide her true nature from the human world but slips up during a full moon. Another could be a love triangle where a human and another supernatural being both vie for the werewolf girlfriend's affections. Or perhaps she's on a mission to protect her human lover from a rival werewolf pack.
One plot idea could be that Erin, after turning into a werewolf, tries to hide it from her family and friends. She struggles with the new instincts and the fear of hurting those she loves. Another idea is that she discovers there's a whole underground community of werewolves and has to learn their rules and ways to survive. Or perhaps she meets a vampire who is intrigued by her new werewolf status and they form an unlikely alliance.
One idea could be a story where a human male stumbles upon a female sergal in a magical forest. They initially have misunderstandings due to their different cultures, but as they spend time together, they learn about each other's ways and develop a deep friendship that could potentially turn into a romantic relationship. Another could be a scenario where the human male is a scientist studying the sergal species and he meets a female sergal who is curious about human technology. They collaborate on a project and during that process, feelings start to grow.
One idea could be that the female extraterrestrial is on a mission to study Earth and she meets a human who helps her understand human emotions. They form a deep bond and have to overcome the differences between their species and the rules of her extraterrestrial society which forbids such relationships.
One plot idea could be Ruby discovering she has werewolf abilities during a mission. She has to learn to control it while still fighting Grimm. Another could be that in a werewolf form, Ruby has enhanced senses that help her track down a powerful and elusive enemy. Or perhaps she forms a pack with some of her friends who also get werewolf-like powers and they have to protect Vale from a new werewolf - Grimm hybrid threat.
One idea could be a Young Justice member getting bitten and turning into a werewolf and having to hide it from the team at first. Another is a werewolf - based villain that the team has to face, who has some connection to an ancient werewolf legend in the DC universe. Maybe a story where a werewolf is used as a weapon by an evil organization against the Young Justice team.