One possible reason could be Sasuke's pursuit of power. In many fanfictions, his thirst for greater strength might lead him to leave Sakura behind as he embarks on a solo journey to train in more dangerous and secluded places. He may feel that his goals are too dangerous for her to be involved with.
Another reason might be related to his past traumas. Sasuke has a lot of emotional baggage from his clan's massacre. He could leave Sakura because he doesn't want to burden her with his inner turmoil. He might think that being alone is the best way to deal with his unresolved issues.
It could also be due to a misunderstanding. Maybe Sasuke misinterprets Sakura's actions or words. For example, if Sakura tries to interfere with his plans in a way he doesn't like, he might decide to leave in a fit of anger, believing that she doesn't understand his true motives.
One possible reason could be his long - standing feelings for Sakura. Despite his journey and time with Karin, his original connection with Sakura might have resurfaced. Sasuke has known Sakura since they were young, and those early memories and emotions could have influenced his decision.
Perhaps Sasuke starts to notice Ino's unique skills and how they complement his own. Ino has her mind - related jutsus which could be useful in certain missions or battles. This practical aspect, combined with a growing personal bond, might lead him to leave Sakura for Ino.
One possible reason could be his strong bond with Naruto. Their relationship has been through so much, and Sasuke might realize that Naruto understands him on a deeper level than Sakura. Maybe he feels that his journey and growth are more intertwined with Naruto's, and he values that connection more in this fanfiction.
There are fanfics like that. Sasuke might leave Sakura for Karin because of Karin's loyalty. Karin has shown unwavering loyalty to Sasuke throughout the series. She was willing to risk her life for him on multiple occasions. In contrast, Sasuke might think that Sakura's love is more of a childhood crush that she hasn't fully grown out of, and he may be drawn to Karin's more mature and selfless loyalty.
In some fanfictions, Sasuke could be under the influence of some dark power or curse. This power might compel him to kidnap Sakura. For example, a dark entity might want to use Sakura's abilities or her connection to Sasuke for its own evil purposes, and Sasuke, being unable to fully control himself, follows its commands.
One possible reason could be a lack of communication. If Sasuke is always away on his missions and doesn't share his thoughts and feelings with Sakura, it can create a rift. Another reason might be differences in their long - term goals. For example, Sakura may want a more stable family life, while Sasuke is still too focused on his pursuit of power or justice in the shinobi world.
One reason could be that Naruto realizes his feelings for someone else and doesn't want to mislead Sakura. In some fanfictions, Naruto might discover that his true love is Hinata and so he steps away from Sakura to pursue a relationship with Hinata without causing any confusion for Sakura.
One possible reason could be that Sasuke is frustrated with Sakura constantly trying to get close to him when he's focused on his revenge. He might yell at her to keep her away and not interfere with his plans.
One possible reason could be Sasuke's continuous absence. He is often away on missions, leaving Sakura feeling lonely and neglected. In fanfiction, this could be exaggerated to a point where she can't take it anymore.
One possible reason could be her long - standing and deep - rooted love for Sasuke. Since childhood, she has had strong feelings for him. Maybe in this fanfiction, she realizes that her feelings for Sasuke are unshakable and that she can't continue to be with Naruto while having such intense feelings for another.