His friends like Hermione and Ron would be deeply affected. They might feel abandoned at first. Hermione, being the logical one, would understand his reasons but still miss him terribly. Ron would probably be more vocal about his sadness and might even try to convince Harry to come back.
The wizarding community as a whole would be in shock. Harry was the 'Chosen One' and his presence had a significant impact on the balance of power. His departure could cause political upheaval. Some might see it as a sign of weakness, while others would respect his decision. Wizards and witches who were counting on him for protection might have to find new ways to defend themselves.
Spike would be heartbroken. He's like Twilight's little brother. He depends on her for guidance and love. If she runs away, he might try to find her on his own and in the process, grow up a bit as he faces challenges alone. He could also feel abandoned and struggle with his own self - worth.
It could make Batman more determined to find him. Batman would be worried about his safety and would start an intense search. He might also feel guilty, thinking that he could have done something to prevent Tim from running away.
For Aunt May, it would be a huge shock. She has already lost so much in her life, and Peter running away would make her feel like she has failed in some way as a guardian. She would probably be constantly looking out the window, hoping to see him come back home. Also, the villains in the story could see his absence as an opportunity. They might become more bold and start causing more chaos in the city, knowing that Spider - Man is not around to stop them.
His friends will surely be worried. They might start looking for him everywhere, feeling sad and confused about why he left. For his closest friends, it could be a very emotional time as they fear for his safety.
His relationship with his teachers could also be affected. Teachers like Dumbledore, who usually encourage students to participate in such events for their growth and development, might be initially concerned or try to persuade him to change his mind. This could cause some tension between them.
His potion - making skills might make him more respected by his classmates. They could come to him for help with their potions homework or for advice on how to improve their own skills.
With his close friends like Ron and Hermione, it might strengthen their bond. They could see it as a sign of Harry's humility and his desire to be more like them. Ron, who has always come from a not - so - wealthy family, might feel a closer connection to Harry. However, with some other characters like the Malfoy family, they might look down on him even more, thinking he has finally fallen from grace.
It could strain his relationships with some pure - blood wizards who are prejudiced against goblins. They might see Harry's trust as a betrayal of wizarding traditions.
Some characters could be angry if they depend on her in some way. For instance, if she was part of a team or a group project, they might feel abandoned. However, it could also give some characters the motivation to change. They might realize they need to be more independent or they might even try to find a way to bring her back.
His friends might become more important to him. Since he is no longer living with his parents, he may rely more on his friends for support and companionship. For instance, he might start spending more time with his best friend, sharing his new living experiences and problems.