In a 'Naruto son of Orochimaru' fanfic, it could start with Naruto discovering his true parentage. This would shock him to the core. Since he is Orochimaru's son, he has access to Orochimaru's vast knowledge of forbidden jutsu. But instead of using them for evil, he wants to use them to protect the Hidden Leaf. He teams up with some of his friends, who are initially skeptical of him. But as they see his good intentions, they support him. He then has to face off against enemies who want to use Orochimaru's legacy for their own dark purposes, and Naruto has to fight to preserve his father's good side (if there is one) and protect his village.
One possible plot could be that Naruto, as Orochimaru's son, struggles with his identity. He might have Orochimaru's scientific genius but also Naruto's determination. He could be shunned by the village at first due to Orochimaru's bad reputation. But then, he uses his unique skills to prove himself, perhaps by developing new jutsu that combines Orochimaru's snake - related techniques with Naruto's own chakra - based powers.
Well, in such a fanfic, the plot might involve Naruto being raised in secrecy by Orochimaru. He would grow up learning Orochimaru's dark arts. However, he has a good heart like the original Naruto. So, he decides to use what he has learned for good. He might go on a journey to find a way to redeem Orochimaru's name in the eyes of the ninja world. Along the way, he faces many challenges from those who fear Orochimaru's influence on him.
One possible plot could be that Naruto, feeling ostracized in Konoha due to his jinchuriki status, decides to join Orochimaru. Orochimaru, seeing Naruto's potential, trains him in some dark and forbidden jutsus. Naruto might start to change, becoming more cynical. He could use his newfound powers against those in Konoha who once shunned him, leading to a series of battles between him and his former friends like Sasuke and Sakura.
Maybe in this fanfic, Naruto has been influenced by some dark force or a traumatic event that makes him turn to Orochimaru. Orochimaru, seeing Naruto's potential, convinces him to work together. Naruto's tasks could involve helping Orochimaru in his experiments. However, as time passes, Naruto realizes the true evil nature of Orochimaru and has to struggle between the loyalty he feels due to the power he's gained and his own moral compass.
A plot twist could be that Orochimaru's transformation into a girl is part of a larger, more complex jutsu that was set in motion long ago. In this new form, she has access to different types of chakra or abilities that she didn't have before. This makes her a target for other villains who want to use her new powers for their own gain, and Naruto has to protect her while also being cautious of her true intentions.
In a fanfiction like this, the plot might involve Orochimaru having some hidden motives in becoming Naruto's 'mate'. Maybe he wants to use Naruto's connection to the Nine - Tails to gain more power for himself. But as time passes, Naruto's positive influence starts to change Orochimaru in ways he didn't expect. Naruto, on the other hand, might see Orochimaru as a project, someone he can reform, and this idea of reforming him could be the basis of their relationship in the fanfiction.
In a fanfiction where Naruto becomes an Orochimaru fan, perhaps Orochimaru has a change of heart and starts to use his knowledge for the good of the village. Naruto witnesses this new side of Orochimaru and is inspired. He begins to study Orochimaru's techniques more closely, believing that he can also use them for good. However, others in the village are skeptical and Naruto has to fight to prove that Orochimaru can be a positive influence.
In this fanfic, Naruto being the son of Thanos could lead to a whole new power dynamic in the Naruto universe. His powers could be a blend of Naruto's chakra abilities and Thanos' strength and reality - warping powers. He may be in a constant battle within himself, as Naruto's values of friendship and protecting the village conflict with the more self - serving and power - hungry aspects of Thanos' nature. He might have to find a way to reconcile these two sides to become a true hero in his own right.
Well, it could be about Naruto being raised in the world of One Piece under Whitebeard. Maybe he'd inherit Whitebeard's strong sense of family and use his Naruto - like skills in that universe. For example, his shadow clone jutsu could be a very unique and useful ability in the pirate world.
Well, it could start with some sort of interdimensional or magical event that links the Naruto and Dragon Ball universes. Maybe Goku somehow ends up in the Naruto world and has a relationship there, resulting in Naruto being his son. Then Naruto could inherit some of Goku's powers, like super strength or the ability to fly, on top of his own ninja skills. He might use these new powers to face even greater threats in the Naruto world, like stronger versions of the Akatsuki.
Well, it could be about Naruto having a different origin as the son of Samul. Maybe it explores how this new identity affects his relationships in Konoha. For example, his friends like Sasuke and Sakura might react differently to him. Also, it could change the way the village elders view him, perhaps with more suspicion or higher expectations.
Well, it could involve Naruto having some unique powers inherited from Kaguya. Maybe he discovers his true lineage gradually and has to deal with the expectations and the secrets that come with it. He might face new enemies who are interested in his connection to Kaguya, or he could use his new - found heritage to bring about a new era of peace in the ninja world.