Sam's mom could also be involved. She might have some old - fashioned remedies that she tries on Sam. And even Gibby could show up and try to make Sam laugh to cheer her up, even if his attempts are a bit on the strange side.
Freddie might also step in. He's good with technology and could use it to research Sam's symptoms and find possible cures. He might also be the one to keep Sam entertained with some of his gadgets while she's sick.
Carly would probably be the first one to take care of Sam. They're best friends, after all. She'd bring her soup and make sure she has enough blankets.
In this fanfiction, perhaps Sam's sickness is something really unique that no one has ever seen before. It could be a magical or science - fictional kind of illness. Her friends could go on a wild adventure to find a cure, traveling to strange places and meeting all kinds of interesting characters along the way.
Her friends could take care of her. For instance, Yuki might bring her some herbal tea that he made himself, believing it would help with her illness.
Thor could be one of the first to take care of Loki. Despite their differences, Thor still cares about his brother. He would use his strength to protect Loki from any threats while Loki is sick and might even search for rare remedies.
Gwen could also take care of Ben. As his cousin, she would be worried about him. She might use her magic to try and ease his symptoms or find a cure. She would probably make him some soup and keep him company while he's sick.
His best friend could be the one to take care of him. This friend would stay by his side, make sure he takes his medicine on time, and keep him company while he's sick.
His teammates, Sasuke and Sakura, would surely be involved. Sasuke, although he may not show it as much, still cares about Naruto. He would keep an eye on Naruto's condition, and if there was any sign of danger, he would be ready to protect him. Sakura would be more hands - on with the medical care, checking his temperature, giving him medicine, and making sure he rests properly.
Sango could also take care of Kagome. As a strong and kind - hearted woman, she would know how to nurse Kagome back to health. She might use her knowledge of herbs and remedies to make Kagome feel better. Plus, she would offer emotional support to Kagome during her illness.
Mr. Burns might try to take care of him. Despite their strange relationship, Burns could feel some sense of responsibility or concern for his loyal assistant.
In this fanfiction, the Chaotix detective agency could also play a role in taking care of Sonic. Vector might not be the best at medical stuff, but he could use his detective skills to find out the source of Sonic's illness. Espio could use his stealth to keep an eye on Sonic's surroundings, and Charmy could keep Sonic's spirits up with his energetic personality.
Alfred would probably be the first one to take care of him. He's always there for Batman.