Sakura could be a main character. She might be the one who takes on a motherly role towards baby Naruto. She'd be very protective and try to teach him basic things. Kakashi could also be important. He'd use his wisdom to figure out how to deal with this situation and also keep an eye on Naruto's safety.
Sasuke could be one of the main characters. He might be initially skeptical or even hostile towards Naruto's mermaid side, but as the story unfolds, he could come to understand and support Naruto. Another character could be Sakura. She could use her medical ninjutsu skills to help Naruto if he gets injured during his underwater adventures.
Samul, of course, since he's Naruto's supposed father in this fanfic. He could be a powerful ninja who had some great influence in the past. Another character could be Naruto's mother, who might have a different story now considering her relationship with Samul. Also, characters like Jiraiya could still play an important role. He might be the one to guide Naruto in understanding his new identity as Samul's son and help him train to face the challenges that come with it.
Hinata is also a likely main character. In the original story, Hinata has a crush on Naruto. With Naruto being a smooth operator, he might notice Hinata's feelings more easily and their relationship could develop in a more romantic and interesting way. Kakashi could also be involved. Naruto could use his smoothness to learn new jutsu from Kakashi more effectively or to get Kakashi to trust him with more important missions.
In addition to the usual suspects, there could be some new characters introduced. For example, an old Pokémon trainer who has seen similar things before and can offer some advice on how to deal with baby Ash. Or a mysterious Pokémon that has the power to either help or hinder the process of getting Ash back to normal.
Tomoyo would also be an important character. She would be very worried about Sakura. She might use her skills in making costumes to create some special baby clothes for Sakura. And she would be constantly by Sakura's side, taking care of her and trying to comfort her.
His friends Orihime and Chad would probably be main characters. Orihime could be very motherly towards baby Ichigo, always making sure he's comfortable. Chad would be the strong protector, making sure no harm comes to the baby.
Besides Naruto, Yugito Nii could be a main character. She is a jinchuriki in Kumo, just like Naruto is in Konoha. They could bond over their shared experiences of being hosts. And there could be some of the Kumo elders who play important roles. They might be the ones who oppose Naruto's entry at first, fearing he could bring trouble, but then as they see how he can contribute to the village, their opinions change.
Well, a Lucario - girl would be a great addition. Lucario is known for its strong fighting and sensing abilities, so the Lucario - girl could be very perceptive and a great fighter. There might also be a Gardevoir - girl. Gardevoir is very elegant and has strong psychic powers. She could help Naruto understand the psychic aspects of the Pokegirl world and be a valuable ally in battles and in deciphering the mysteries of this new adventure.
The street kids themselves would be main characters. They could be a diverse group with different personalities and backstories. There might also be Naruto's friends like Sakura and Kakashi who could play important roles. Sakura could help with the kids' medical needs, and Kakashi could offer his wisdom in training the kids.
Sakura could be a main character. Since it's Naruto returning to Konoha, Sakura, being his friend and a strong ninja in her own right, might play a big role. Maybe she's the one who first welcomes Naruto back and they team up to face any threats.