One possible plotline could be Naruto growing up with a sense of deep abandonment and having to face the world alone. This could lead to him having a much more cynical view of life. He might struggle more with controlling the Kyuubi's power as he has no guidance from Kushina. Another aspect could be his relationships with other characters like Iruka or Sasuke being different. Without Kushina's love, he may be more desperate for any form of connection.
Perhaps in this fanfiction, Naruto would start to resent the village more. Since Kushina abandoned him, he might feel that the village didn't do enough to protect him either. He could be more likely to side with those who oppose Konoha. Also, his training with the Kyuubi's power would be a solitary journey. He might accidentally release the Kyuubi more often, causing chaos in the village which further isolates him.
The story could also explore how Naruto discovers the reasons behind Kushina's abandonment. Maybe it was due to some dark secret in the village or a threat that she thought would harm Naruto if she stayed. With the Kyuubi inside him, he could be seen as a target. This discovery could then lead to Naruto having to make a choice between forgiving Kushina and the village or seeking revenge.
A possible plotline is that Naruto gets adopted by a group outside the village. He grows up learning their ways and becomes a sort of outcast from Konoha. Then, he could return to the village with a different set of skills and a new perspective. Or, he might develop a vendetta against Konoha for allowing his abandonment and try to take revenge in some way.
One possible plotline could be that Naruto is kidnapped by Kyuubi to gain some sort of power or knowledge from him. Maybe the Kyuubi believes Naruto has a secret that can help it break free from its current state. Another could be that Naruto is kidnapped as a way to get back at the Hidden Leaf Village, and the Kyuubi uses Naruto as a bargaining chip. It could also be that there is some external force that makes the Kyuubi kidnap Naruto, like a dark wizard or something similar that has control over the Kyuubi.
A plotline could be that Naruto has to keep his true parentage a secret for a long time. This secrecy adds to his internal conflict as he tries to fit in with the other ninjas. As the son of Kyuubi and Kushina, he may be hunted by certain groups who want to either use his power or destroy it. He then has to go on a quest to find out more about his parents and his own identity, all while fending off these threats.
One possible plotline could be Naruto feeling extremely lost and having to find his own way to become stronger without their guidance. He might start to question his own worth and abilities, but then he could meet new allies who help him realize his true potential on his own. For example, he could encounter some other outcast ninja who have their own unique skills and together they form a new kind of ninja team that challenges the traditional ways of the ninja world.
One possible plotline could be that Naruto's family is in a difficult situation and they believe they can only support his sister. So, Naruto is left on his own. He then has to struggle to survive in the ninja world without the support of his family. He might become more independent and self - reliant, forging his own path.
Well, it could start with the fem Kyuubi being in love with Naruto. Since she has negative feelings towards Kushina, she could begin by influencing Naruto's view of his mother. For example, she might show Naruto 'alternate' versions of Kushina's past actions that are not entirely true. As the story progresses, the fem Kyuubi could try to isolate Naruto from anything related to Kushina, like the Uzumaki clan heritage that Kushina represents. And perhaps, in the end, she realizes the error of her ways when Naruto discovers the truth about his mother. However, this is just one possible set of plotlines in such a complex and potentially controversial fanfiction concept.
One possible plotline could be that Naruto is somehow transported back in time and has to fight Kushina in a misunderstanding. Maybe he's mistaken for an enemy due to some time - warp magic or jutsu gone wrong. Another could be a scenario where Kushina is controlled by an evil force, and Naruto has to fight her to break the control. Or perhaps it's a sparring match in a dream world where Naruto and Kushina test each other's skills without real harm.
One possible plotline could be that Naruto discovers some long - lost secret about his mother Kushina and decides to leave the village with her to explore this mystery further. Maybe they are on a quest to find some hidden power or knowledge that is related to Kushina's Uzumaki heritage.
One possible plotline could be Naruto growing up on his own, learning survival skills at a very young age. He might become more cynical towards the idea of family. Another could be that he meets someone who becomes like a surrogate family, and through this relationship, he starts to heal his inner wounds. He could also start to search for the reasons why his family abandoned him, leading to a journey of self - discovery.
Perhaps Naruto, after being abandoned by Minato, falls in with a group of outcasts. Together they form a sort of family of their own. Naruto's natural leadership and kind heart start to shine through as he tries to protect this new family. As he uncovers more about his past and Minato, he has to decide whether to forgive his father or hold on to his anger. This internal struggle could be a major part of the fanfiction.