Another possible antagonist could be a powerful ghoul organization that wants to use Kaneki for their own purposes. They might try to capture him and experiment on him to figure out how to create more half - humans or use his powers for their own gain. They don't care about Kaneki's well - being and are only interested in what he can do for them.
Well, one possible plot could be that Kaneki struggles to fit into both the human and ghoul worlds from the very start. Since he's born a half - human, he might have some unique powers or abilities that neither humans nor ghouls fully understand. Maybe he tries to use his position to bridge the gap between the two warring species, facing a lot of opposition from both sides.
The old - fashioned and conservative gods who don't like the idea of a new, young god like Percy shaking up their established order could be antagonists. They might see him as a threat to their power and try to undermine him.
Perhaps there could be some overseers or enforcers who are especially brutal towards the slaves. They might take pleasure in punishing the slaves and would be a major obstacle for Harry. These characters could be loyal to the slave - owning system and do everything to maintain it, seeing any sign of resistance from Harry as a threat.
Another vampire, an older and more powerful one, could be an antagonist. This vampire might see Percy as a threat to his power or territory. Maybe he wants to either kill Percy or make him submit to his rule.
A group of vampire hunters could also be the antagonists. They might not be able to tell the difference between Issei and a full - blooded vampire and target him. They could be very zealous in their mission to wipe out all vampires and view Issei as just another one to be hunted down.
The East India Trading Company could still be a major antagonist. They might be even more determined to capture Jack Sparrow, especially if they discover his non - human nature and fear what he could do. They would see him as a threat to their control over the seas and trade.
Another possible antagonist could be some of the more power - hungry Titans. They might see Percy as a rival or someone who could disrupt their plans. They could try to manipulate him or turn him to their side, and if he refuses, they would become his enemies. Also, there could be some ancient monsters that sense Percy's new power and want to destroy him before he becomes too powerful.
The Titans could be great antagonists. They might see Percy as a threat to their plans of overthrowing the gods again. Since Percy has chaos powers, they could fear that he could disrupt their carefully laid - out schemes. Another possibility is some of the more traditional enemies of the demigods, like the monsters. They might be drawn to Percy's chaotic energy and try to either consume it or destroy him to prevent him from becoming too powerful.
The main antagonists could be the villagers who fear Naruto's mini Kyuubi form and try to drive him out of the village. Their prejudice and fear act as a major obstacle for Naruto, who just wants to be accepted.
The traditional Titans could be antagonists. Since Percy has only half - Titan blood, they might see him as a threat or a tool to use against the gods. Kronos, if he were to somehow return or have a remnant of his power, would be a powerful foe. He could try to manipulate Percy's Titan side to turn him against the gods.