Well, in such a fanfiction, perhaps Michael is hurt during a fight with some inmates who are against his escape plan. Sarah, who has always been by his side in spirit if not physically all the time, immediately steps in. She might move heaven and earth to get him proper medical attention. She could also be very protective in terms of keeping his secrets safe so that his overall plan doesn't get derailed because of this unexpected setback.
In the fanfiction, Sarah might protect Michael by creating diversions. Say Michael is hurt and needs to rest in a hidden place. Sarah could start a small commotion elsewhere in the prison to draw guards' attention away from where Michael is recuperating.
One possible fanfiction could be that Dean gets seriously injured during a hunt. Castiel, feeling a deep sense of protectiveness, uses his angelic powers to heal Dean as much as he can. He then stays by Dean's side, warding off any potential threats, whether they be other supernatural creatures or even humans with bad intentions. Castiel refuses to leave Dean's side until he's fully recovered, and in the process, their relationship deepens, with Dean realizing just how much Castiel cares for him.
One possible fanfiction could be that Stiles gets injured during a fight with a supernatural creature. Scott, being his best friend and a werewolf, immediately goes into protective mode. He uses his enhanced senses to track down any remaining threats and then stays by Stiles' side at the hospital, growling at anyone who seems to pose a danger to his friend. He even shares his werewolf strength to help Stiles heal faster, in a very subtle way that no one else notices.
One possible fanfiction could be that Merlin gets injured during a battle while trying to protect Arthur. Arthur then becomes extremely protective, refusing to let anyone else tend to Merlin's wounds. He stays by Merlin's side, worried sick, and vows to be more careful in the future to prevent Merlin from getting hurt again.
One possible fanfiction could be where Stiles gets injured during a fight with a supernatural creature. Derek, who has grown to care for Stiles deeply, immediately goes into protective mode. He growls at any potential threats, and takes Stiles to a safe place. He then uses his werewolf abilities to heal Stiles as much as he can, all while Stiles is looking at him with a mixture of pain and admiration.
Well, it could start with Loki getting physically and emotionally hurt by the taunts of the other Asgardians. Thor, noticing Loki's distress, steps in to protect him. He defends Loki in front of the court and makes it clear that Loki is his brother and should be treated with respect. Then, Thor takes Loki away to a quiet place where Loki can heal. He offers Loki comfort and support, and together they start to repair their relationship which had been strained in the past.
Sara Tancredi is a very popular character to be paired with Michael. Their relationship in the original show was complex and in fanfiction, it can be further explored, especially in the context of Michael being hurt. Another one could be his brother Lincoln, as they have a deep bond and Lincoln is often there to support or be involved when Michael is in trouble.
One common theme could be his emotional pain during his time in prison. For example, the isolation he felt from his family and friends outside. Another theme might be physical hurt he endures during his various escape attempts and confrontations with other inmates or prison guards.
In a fanfiction scenario, Damon might be hurt by a spell that was meant for Stefan. Stefan, feeling guilty and protective, devotes all his time to finding a cure for Damon. He goes on a journey, facing many challenges along the way, and in the end, he manages to break the spell and save Damon, strengthening their bond in the process.
In some Horseland fanfiction where Sarah gets hurt, her friends might rally around her. They could bring her to the stables' makeshift infirmary. The horses might also sense her distress and become unusually calm around her as if trying to comfort her.