He might move away because he is seeking a new purpose in life. Naruto has always been defined by his connection to Konoha, but he could be looking for something more. For example, he could be on a journey to discover more about his family's past, which might lead him away from Konoha. Also, there could be political unrest in the village that he doesn't want to be part of, so he decides to leave.
One reason could be that he feels misunderstood by the villagers. Despite all he has done for Konoha, some still hold grudges or are afraid of his power. Another might be that he wants to explore the world on his own terms, away from the responsibilities and restrictions of Konoha. Maybe he also feels a sense of loneliness there, as he has lost many important people and the village constantly reminds him of those losses.
One possible reason could be that he felt misunderstood. In the village, Naruto was often ostracized despite his good intentions. Maybe he got tired of trying to prove himself and just ran away. For example, when the villagers still saw him as the nine - tailed fox rather than Naruto, it might have pushed him to leave.
One possible reason could be feeling ostracized. In the Naruto world, being different is often not easily accepted. As a female Naruto, she might face even more scrutiny and prejudice. Maybe she's tired of the constant expectations and the way she's treated in Konoha, so she decides to run away to find a place where she can be herself.
It could be that Naruto discovers some secrets within his family that make him feel uncomfortable or out of place. For example, if there are hidden agendas or dark pasts that he doesn't want to be associated with, he might choose to move away to start anew.
One possible reason could be the pressure he feels in Konoha. Naruto has always been an outcast in the village to some extent. People used to fear and shun him because of the Nine - Tails inside him. He might feel that running away would be a way to escape all that negative attention and find a place where he could be himself without the constant reminder of his 'otherness'.
Another reason could be related to a prophecy or a hidden mission. They might have learned about a prophecy that required them to leave Konoha in order to fulfill it. This could involve finding a powerful artifact or learning a special technique that could only be achieved by being away from the village. Their departure would then be a sacrifice for the greater good of not just Konoha, but the entire ninja world.
His departure would definitely put a strain on his relationships. His close friends like Sasuke, if he is back in Konoha at that time, would have mixed feelings. They might worry about Naruto but also be a bit angry that he left without consulting them. Naruto's younger friends like Boruto would be confused and miss him a great deal, and this could lead to some distance in their relationships.
One possible consequence could be that Naruto grows up away from the influence of Konoha's shinobi culture. He might develop a different set of values and skills. For example, without the guidance of Iruka and Kakashi, his understanding of ninjutsu and teamwork could be very different. Also, his relationships with characters like Sasuke and Sakura would be greatly affected. Maybe he wouldn't have the same rivalry with Sasuke, and his bond with Sakura might not even form.
From a security perspective, Konoha would be weaker. Naruto is a very powerful ninja, and Hinata is no slouch either. Their skills and abilities would be missed. Enemies might see this as an opportunity to attack Konoha. Also, Naruto has been a symbol of hope for the village. His departure could lead to a decrease in morale among the villagers. They might start to feel less secure and more pessimistic about the future.
It would create a sense of panic. Naruto is a very important figure in Konoha. His strength has been crucial in protecting the village. Without him, the villagers would fear attacks from other villages or threats from the Akatsuki. For instance, if the Akatsuki knew Naruto had left Konoha, they would likely see it as an opportunity to capture him more easily.
One possible reason could be that Hermione wants to pursue her own independent magical research. She is highly intelligent and may feel the need to focus on her studies without the distractions that come with being close to Harry. Another reason might be a disagreement over some major decision in the wizarding world. For example, if Harry has a different stance on how to deal with the remaining Death Eaters or how to reform Hogwarts' curriculum, Hermione, with her strong opinions, may choose to distance herself to avoid constant conflict.