It could be a powerful ninja who has made a deal with an otherworldly force to gain powers to match Naruto's. This antagonist might be jealous of Naruto's unique heritage and wants to prove that pure ninja power is superior. So, he uses dark magic or forbidden jutsu to become a formidable foe.
A group of rogue ninjas could be the main antagonists. They fear Naruto's new powers and think he will use them to take over. So, they band together and form an alliance with some dark entities. They use their combined skills and the power of these entities to try and take Naruto down. They also start spreading false rumors about Naruto to turn the other villagers against him, creating a situation where Naruto has to not only fight them physically but also clear his name.
Well, it could be about Naruto having the powers of both Saiyan and Kryptonian. Maybe he can use Saiyan's ability to transform into a Super Saiyan and combine it with Kryptonian super strength, heat vision, etc. He could use these combined powers to protect the Hidden Leaf Village from a new kind of threat that no one in the Naruto universe has ever faced before.
It could be a powerful ninja from another village who is jealous of Naruto's half - demon half - god powers. He might see Naruto as a threat to his own village's dominance and try to eliminate him.
Maybe a rogue ninja who has been experimenting with dark magic. He discovers Naruto's unique nature and wants to steal his power. He believes that by combining Naruto's angel and demon fox powers, he can become invincible. So, he sets out to hunt Naruto down and tries every trick in the book to get his hands on that power.
Sure, there are probably fanfictions with this concept. Fanfic writers are known for their creativity in crossing over different fictional worlds. A 'Naruto is half Saiyan' story could explore how Naruto's life and the Naruto - verse in general would be affected. For example, how would his relationships with his friends and enemies change? How would the ninja world react to his new Saiyan abilities? It could also delve into the backstory of how he came to be half Saiyan, perhaps some kind of inter - dimensional or time - traveling event.
It could be a powerful wizard who fears Harry's half - demon powers and wants to eliminate him. This wizard might see Harry as a threat to the wizarding world's order.
It could be an evil Saiyan who comes to the Naruto world to cause chaos. Maybe he's a rogue Saiyan who was exiled from his own planet and wants to take over Naruto's world.
Orochimaru would be a great main antagonist. He's always been interested in power and the secrets of the body. Naruto's half - demon fox nature would be a prime target for his experiments. He could try to extract the power of the demon fox from Naruto, or use Naruto as a way to create his own brand of super - soldiers with demon - like powers.
It could be a dark sorcerer who has been studying the secrets of angels and vampires. He discovers Naruto's existence and wants to use him as a key ingredient in a dark spell. The sorcerer is power - hungry and believes that by harnessing Naruto's half - angel half - vampire essence, he can open a portal to a dimension filled with dark magic and bring chaos to the ninja world. He would be constantly devising traps and sending minions after Naruto to capture him.
It could be a rogue god who sees the half - robot as a threat to the natural order. They might try to destroy it because they don't like the idea of a half - human, half - machine being in the world of demigods. Another possibility is a powerful Titan who was awakened and wants to use the half - robot's technology for their own evil purposes. Maybe the half - robot has some sort of power source that the Titan desires.
A powerful and ancient Kryptonian entity that was sealed away long ago could be the main antagonist. It breaks free due to some events and wants to reshape Krypton according to its own dark desires. The reborn character, with their new - found powers and different perspective, stands in its way. Also, there could be a group of Kryptonian zealots who oppose any change in the traditional Kryptonian ways. They see the reborn character as a threat to their way of life and try to get rid of them.