A possible plot is that there's a mysterious force that is causing glitches in both the Hetalia and Homestuck universes. Characters from both have to team up to figure out what's going on. The Hetalia characters could bring their political and diplomatic skills to the table, while the Homestuck characters offer their knowledge of the complex and often absurd rules of their world. Maybe some of the Hetalia characters get sucked into the Homestuck's session - like gameplay, and they have to learn how to level up and fight enemies in that context.
One idea could be to have the characters from Hetalia and Homestuck participate in an international event together. For example, a global gaming tournament where the strategic minds of the Hetalia characters and the unique abilities of the Homestuck characters collide. Another plot could involve a dimension - hopping adventure where the Hetalia countries find themselves in the Homestuck universe and have to adapt to its strange rules and customs while trying to find their way back home. Or perhaps a story where the trolls from Homestuck end up in the Hetalia world and start causing chaos among the different nations.
One idea could be a sports competition between the characters from Hetalia and Countryhumans. They could compete in various events like a grand international Olympics - style tournament. This would bring out their competitive sides as well as show their national pride. Another plot could be a diplomatic crisis where the characters from both universes have to work together to solve a global issue, like a sudden environmental catastrophe that affects all of their 'countries'.
One idea could be that the characters from Hamilton are transported to the Hetalia world. Hamilton could use his political acumen to influence the international relations in the Hetalia universe. For example, he might try to introduce new democratic ideas among the nation - states there.
One idea could be that the countries from Hetalia are somehow transported into the Naruto world. For example, Italy could end up in Konoha and his carefree attitude might amuse or annoy the ninja there. Maybe he gets involved in a mission by accident and his unique skills from being a nation, like his knowledge of different cultures and languages, could come in handy. Another plot could involve Naruto being sent to the Hetalia world and having to deal with international relations in a very different way than he's used to in the ninja world. He might try to use his ninja way to promote peace between the nations there.
One plot idea could be that the characters from Good Omens and Homestuck find themselves in a shared alternate universe. The angels and demons from Good Omens might be quite confused by the strange and complex world of Homestuck, while the Homestuck characters could be intrigued by the celestial beings. For example, Crowley could team up with a Homestuck troll to outwit some overzealous angels. Another idea is a crossover where they have to solve a mystery that spans both their universes. Maybe a powerful artifact has been stolen and its pieces are scattered across both worlds, forcing the characters to cooperate despite their differences in nature and origin.
Maybe the Sburb game from Homestuck starts to affect the Marvel universe. The Guardians of the Galaxy could be drawn into it, thinking it's some new cosmic threat. The Homestuck trolls' hemospectrum - related powers could interact in strange ways with the superpowers in the Marvel world. For instance, a high - blood troll's strength might be compared to that of the Hulk.
One idea could be that the characters from Homestuck end up in the Underground of Undertale. They might have to deal with the various monsters there while also trying to find a way back home. Maybe John Egbert could team up with Frisk and they use their unique abilities to overcome challenges like puzzles and battles.
Maybe the Black Butler characters are sent to the Hetalia world. Sebastian could be intrigued by the different cultures and politics of the countries. He might use his charm and skills to manipulate some of the smaller countries for his own or Ciel's gain. Grell could go wild with excitement over all the new 'pretties' he could potentially reap in this new world filled with so many different characters. And Ciel would be constantly trying to figure out how to get back to his own world while also dealing with the strange international relations in Hetalia.
One idea could be a Quidditch tournament where the Hetalia characters represent different magical countries. For example, Italy could be on a team and use his charm to distract the opposing team. Another could be a magical artifact that gets lost in the Hetalia world and the Harry Potter characters have to go there to retrieve it. Maybe they have to deal with the political situations in the Hetalia world while searching for the artifact.
One idea could be to have Sherlock investigate a mystery related to a historical event in Hetalia. For example, he could look into the disappearance of a valuable artifact during a time of war in one of the Hetalia countries. Another idea is to have the Hetalia characters assist Sherlock in solving a case in London. Maybe Italy could provide some unexpected insights with his unique perspective. Also, a crossover could involve Sherlock being transported to the Hetalia world and having to adapt to its strange rules and cultures while still using his detective skills to solve local mysteries.
One idea could be that the Hetalia characters suddenly find themselves in the BNHA universe and have to adapt to having quirks. For example, Italy might be really confused at first but then find that his ability to make good pasta could be turned into a quirk related to food creation or manipulation. Another could be that the BNHA characters visit the Hetalia world and are shocked by the different cultures and historical settings. They could learn about different forms of power and leadership from the Hetalia characters.