It could be a new character introduced in the fanfic. Maybe a fellow scientist who is envious of Bulma's fame and success. This new character could pretend to be her friend, gain her trust, and then steal her research data or sabotage her experiments, thus betraying her.
Yamcha could potentially betray Bulma. Even though they have a history together, in a fanfic scenario, he could be jealous of Bulma's growing closeness with Vegeta or her scientific achievements. So, he might do something to undermine her, like spreading false rumors about her work.
Well, it could be about Bulma being betrayed by a close friend in the Dragon Ball universe. Maybe that friend reveals her secrets to an enemy, like her latest inventions or the location of the Dragon Balls she was guarding. This would put her in a dangerous situation and lead to a series of adventures where she has to fix the mess.
Frieza could be a great antagonist. He has a history with Broly and would be interested in Bulma's technology. He might see Broly's new alliance with Bulma as a threat and try to break it up. Frieza could also want to use Bulma to create powerful weapons or devices for his own evil purposes.
Trunks could be an interesting fusion partner for his own mother. This would create a really complex character. They share a lot of knowledge about the future already. Fusing could enhance their ability to prevent disasters in the future timeline even more, perhaps by creating a time - shield that can protect the future from any time - traveling villains.
It's also possible that there are family or relationship issues at play. If there are conflicts within her family or with her partner, she may choose to hide the pregnancy and move out to avoid the stress and figure things out on her own terms. For example, if her partner is not ready for a child and she is, she might need some space to decide what to do next.
The plot might involve Bulma creating a new device that has some unexpected side effects. Gohan then comes to help her fix it. Along the way, they might encounter some old enemies or new threats. And perhaps through this experience, they develop a deeper understanding and friendship. For example, Bulma could be working on a time - travel device and accidentally sends them both to a different era, where they have to rely on each other to get back home.
Bulma would be a main character. Another could be Goku. Even though Goku is more known for his pure heart and fighting skills, a fanfic could explore a scenario where his scent has an unexpected effect on Bulma. It could be a different take on their relationship within the Dragon Ball universe and add a whole new layer of intrigue to the story.
Vegeta would be a likely candidate. Given his complex relationship with Bulma in the original series, a fanfic about 'conquering' Bulma could center around him as he tries to better understand and connect with her on a deeper level.
In such fanfics, Bulma might be portrayed as more adventurous in her love life. She could be shown as being open to new relationships outside of her usual circle, which might bring out different aspects of her personality, like her boldness or her ability to adapt to new situations.
Perhaps Goku. Goku has a big heart and he's always ready to help those in trouble. He could sense Bulma's distress and come to her aid.
It could be Frieza. He might see Bulma as a valuable asset due to her intelligence and knowledge of Earth's technology. He could kidnap her to use her to build powerful weapons or devices to help him regain his power and dominance in the universe.