Well, there could be an evil scientist in the fanfiction. This scientist might be researching the power of hypnosis on Pokemon trainers and sees Iris as a perfect test subject. They would use their advanced technology and knowledge of Pokemon behavior to hypnotize her. Also, a powerful psychic - type Pokemon that has gone rogue could be an antagonist. It might hypnotize Iris to do its bidding, like stealing other powerful Pokemon or causing chaos in Pokemon battles. And don't forget about a group of treasure hunters who want to use Iris's hypnotized state to find a hidden treasure that only she knows the location of through her adventures.
A mysterious organization that wants to control the Pokemon world could be the antagonists. They hypnotize Iris as part of their grand plan to disrupt the balance. They might think that by controlling her, they can influence the other strong Pokemon trainers. Another potential antagonist is a jealous rival of Iris. This rival, who has always been in her shadow, teams up with a Pokemon that can hypnotize to make Iris look bad in front of everyone and lose her confidence. There could also be a Pokemon spirit from an ancient era that is awakened and hypnotizes Iris to bring back the old ways of the Pokemon world, which are not in line with the current harmony.
Team Skull could be a great antagonist. They might be after a special Pokemon that Lillie has or they could be causing trouble in the regions she travels through in the fanfiction. Their rowdy and unruly behavior would pose a threat to Lillie and her Pokemon.
One type of antagonist could be a corrupt Pokemon League official. In the fanfic, this official might bribe Ash to do something unethical, like throwing a battle against Iris. When Iris finds out, she'll feel betrayed. Another likely antagonist is a Pokemon hunter. If the hunter captures a Pokemon that Ash and Iris both care about, and Ash, in an attempt to rescue it, makes a deal with the hunter that seems to go against Iris's values, she'll feel betrayed. And sometimes, it could be a self - centered Pokemon trainer who wants to be the only star. They might set up Ash and Iris to fight each other and make it look like one has betrayed the other.
Well, perhaps Iris is hypnotized during a Pokemon contest. She starts to act out of character, making strange commands to her Pokemon. This could lead to her Pokemon being confused at first, but then they try to break the hypnosis by using their strong bond with her. Another plot might involve an ancient artifact that hypnotizes Iris and transports her to a different dimension where she has to find a way to break free and return to her own world, all while dealing with strange and powerful Pokemon in that other dimension.
A new and original antagonist could be a rogue psychologist who has developed a powerful hypnosis technique. This character might be jealous of Peter's abilities and want to use hypnosis to take over his mind and use his powers for their own gain. Or it could be a secret organization that wants to use Peter as a weapon, and they use hypnosis as a means of control.
One potential antagonist could be a rogue ninja who also has aerokinesis but uses it for evil. He might be jealous of Naruto's natural talent and try to undermine him at every turn. Another could be a powerful sorcerer from a far - off land who has come to the Naruto universe specifically to find someone with aerokinesis to either steal their power or use them as a tool. There could also be a group of anti - ninja who see Naruto's new power as a threat to their plans of overthrowing the ninja system and they try to eliminate him.
Perhaps Orochimaru could still be an antagonist. In this fanfiction, he might be jealous of Naruto's new god - like gaming powers and try to steal them for his own experiments.
There could be a jealous fellow ninja from within the village who feels that Naruto is getting too much attention for his blade - mastery. This ninja could turn against Naruto and become an antagonist, perhaps even teaming up with external forces. Also, an ancient evil entity that was sealed away long ago might be awakened by the power of Naruto's blade and seek to destroy him and the village to regain its freedom.
It could be some of the hospital's board members who might not approve of their relationship and Cameron's pregnancy while working at the hospital. They could try to make things difficult for the couple.
There could be new antagonists created specifically for this fanfiction. Maybe some other ninja from a far - off land who are jealous of Naruto's power. They could come to the Hidden Leaf Village to challenge Naruto and steal his speed - related secrets.
Cell could also be an antagonist. He has an interest in powerful Saiyan genetics. The baby, being related to Goku, would be of great interest to him. He might try to absorb the baby to gain even more power, creating a big conflict for the heroes to deal with.