It could be a group of friends. Each friend might have a different reaction to the pokemon showing up in real life. One could be super excited and want to catch them all, another might be more cautious and worried about the potential dangers. Together, they would navigate the new world where pokemon and humans meet, having adventures and learning important lessons along the way.
The main characters would surely include Ash. In Pokemon Red, the rival character, Gary (or whatever name you choose for the rival in the game), could also play a major role. And of course, the various gym leaders from Pokemon Red. They could have different encounters with Ash, some might be friendly and help him, while others could be more challenging opponents. Also, Professor Oak might be involved, as he is connected to both Ash's world and the world of Pokemon Red in some ways.
In these fanfics, the main characters can vary widely. One type is the Pokemon trainer - turned - real - life - hero. They are usually kids or teens who already have some knowledge of Pokemon from games or shows and are quick to adapt. They might be joined by their friends or family members. Also, there could be characters who are initially skeptical about Pokemon in real life but then become believers and important parts of the story. For example, a journalist who at first thinks it's all a hoax but then discovers the truth and helps spread the word about Pokemon in the real world.
Obviously, Naruto and Jiraiya would be the main characters. Naruto, the protagonist of the original series, and Jiraiya, his mentor. They have a deep connection, and any fanfiction about them meeting would revolve around their relationship.
Well, obviously Nero and Sparda are the main characters. Nero, with his white hair and his Devil Bringer arm, is a key figure in the Devil May Cry series. He's known for his brashness and his strong sense of justice. Sparda, on the other hand, is a legendary demon. He's the father of Dante and Vergil. He's a very powerful and mysterious character. In this fanfiction, their encounter would be the central focus, and their different personalities and powers would drive the story forward.
Obviously, Draco Malfoy and Dudley Dursley are the main characters. Draco, with his blond hair and aristocratic air, is a well - known Slytherin from the Harry Potter series. Dudley, on the other hand, is Harry's cousin, a rather large and spoiled Muggle boy. Their encounter would be the central focus of this fanfiction.
Most likely, Tom from Tom's world and Edd from Edd's world would be main characters. They are the central figures in their respective worlds and would probably drive the story forward when the two worlds meet.
The main characters are Yugi and Yusaku. Yugi is a character with a long history in the Duel Monsters universe. He has a group of friends and has faced many challenges. Yusaku, on the other hand, is more of a loner who uses his hacking skills in dueling. In the fanfiction, they will be the central focus as their paths cross and they interact with each other. Their different personalities and dueling styles will drive the story forward, whether they become friends, rivals, or a combination of both.
Obviously, Percy would be one of the main characters. And of course, the gods would play important roles too. Gods like Zeus, Poseidon, and Athena are likely to be there. Percy's friends from the demigod world, like Annabeth, might also make appearances.
Obviously, Naruto would be one of the main characters. He's the central figure from the Naruto universe. And then there would be the Pokegirl. She could be any type of Pokegirl, like a Pikachu - girl or a Charmander - girl. Their different personalities and abilities would drive the story forward.
Obviously, Obito is one of the main characters. He has a complex backstory and his presence is bound to have a big impact on the Akatsuki.