In the fanfiction, they could face the challenge of forging new alliances. Since they left Konoha, they need to find new friends or partners who can help them in their journey. However, it's not easy to trust new people especially when they are seen as deserters from their own village. And they also need to constantly prove themselves to these new potential allies, which can be a very difficult and time - consuming process.
One major challenge could be dealing with new enemies. Outside of Konoha, there are different ninja clans and organizations that may not be friendly. They have to adapt to new fighting styles and strategies of these opponents. For instance, they might encounter powerful rogue ninjas who are more ruthless than the ones they faced in Konoha. Another challenge is that they may have to deal with their own internal conflicts while on the road. Naruto might struggle with feelings of homesickness and Sasuke with his inner demons related to his past and his thirst for revenge.
In the ANBU after leaving Team 7, Naruto will be confronted with numerous challenges. Physically, the missions are likely to be more intense, requiring him to further develop his skills and combat abilities. He'll need to learn new stealth techniques and master different types of weapons. Emotionally, he'll face isolation. ANBU work is solitary, and Naruto, who thrived on the camaraderie of Team 7, will have to adjust to being alone most of the time. Additionally, he'll be faced with complex political situations within the ANBU organization. He'll have to navigate through power struggles and different factions, all while trying to stay true to himself and his values.
On the other hand, their relationships could grow stronger. Away from the rules and expectations of Konoha, they rely more on each other. Naruto and Sasuke could finally understand each other better. Sakura, with her medical skills, becomes even more important to them. They start to trust each other more deeply, and their bond as a team becomes unbreakable. They might have heart - to - heart conversations that they never had in Konoha.
Their relationship would go through several stages. Initially, there would be a sense of unease as they are leaving their home. However, as they journey on, they will encounter various difficulties. For example, when they are short on food and supplies, they have to work together to find resources. This kind of shared experience would make them more empathetic towards each other. Sasuke, who has always been reserved, might open up more about his family and his quest for revenge in a more sincere way to Naruto. Naruto, in turn, would share his insecurities about being the Jinchuriki. Over time, their relationship would evolve from comrades to true friends who are willing to sacrifice for each other.
The main challenges would likely be navigating Danzo's complex web of intentions. Plus, they'd have to adapt to a training style that might push their limits and deal with the potential backlash from the rest of the village for working with Danzo.
One possible plot twist could be that they are being secretly manipulated by an unknown enemy who wants them out of Konoha for some dark purpose. Maybe this enemy has spread false rumors about them in the village, making them feel like they have no choice but to leave. Another plot twist might be that they discover a long - hidden truth about their families that is connected to some ancient power outside of Konoha, which compels them to leave in search of answers.
One possible plot could be that they leave Konoha due to a new threat that the village is unable or unwilling to face. They might go on a journey to find a way to defeat this threat on their own. Along the way, they could face many challenges that test their friendship and skills.
In a fanfiction, after their wedding, Sasuke and Female Naruto might face the challenge of balancing their duties. Naruto might want to focus on village improvements while Sasuke may be more interested in security matters. This difference in priorities could lead to arguments. Also, Sasuke has a dark past that still haunts him at times. His nightmares could potentially affect their relationship. Moreover, they will have to deal with the expectations of the village. People will look up to them as a couple, and any mistake they make could be highly scrutinized, adding stress to their married life.
One challenge could be dealing with the post - war trauma. Ron might have nightmares about the battles, and Hermione would have to be there to comfort him. Also, they might face difficulties in adjusting to the new normal in the wizarding world, like new laws and social changes.
They might face discrimination from other villages. Since they are from Konoha, other villages may be suspicious of them and not trust them easily.
One challenge could be loneliness. Without other males around, he might struggle to find that sense of brotherhood or male camaraderie. He may feel isolated in some ways.