One interesting storyline could be Ash befriending Mewtwo in a more in - depth way. Maybe Mewtwo decides to travel with Ash and his team, and they face challenges together. Ash could help Mewtwo understand the true meaning of friendship and trust, which Mewtwo has always struggled with due to its creation and past experiences.
Another storyline could be Mewtwo using its powers to protect Ash from a powerful and mysterious new villain. This would show a strong bond between them. Mewtwo might have to make sacrifices to keep Ash safe, like using up a lot of its energy or putting itself in danger. And in the process, Ash could also grow stronger and learn new strategies from Mewtwo.
In some fanfictions, the OC might be a Pokemon with a special power that Mewtwo is interested in. For example, the OC could be a shiny Pokemon with the power to heal other Pokemon instantly. Mewtwo wants to study this power and in the process, they become friends. They then team up to help other Pokemon in need, like those that have been affected by pollution or are being hunted by poachers.
In some fanfictions, there could be a backstory where Amber was involved in the creation or discovery of Mewtwo in some way. This could lead to a complex relationship where Mewtwo has mixed feelings towards Amber. On one hand, he might feel a sense of loyalty or connection because of their past, but on the other hand, he could also be wary due to the circumstances of his creation. They then have to navigate these feelings while also dealing with external challenges in the Pokémon world.
One interesting storyline could be Ash and the female Mewtwo forming an unlikely friendship. They could start off as strangers, with Mewtwo being cautious of Ash due to her past experiences with humans. But as Ash shows kindness and understanding, they gradually grow closer. For example, Ash could help Mewtwo when she is injured in a battle against a powerful enemy. Another could be a story where they team up to save the Pokémon world from a new, mysterious threat that neither of them could face alone.
A possible plot is that Ash, while in Mewtwo's form, is hunted by those who fear Mewtwo's power. He has to use his own knowledge of friendship and teamwork, which is so characteristic of Ash, to convince the people and Pokemon around him that he's not a threat. This could lead to some really cool battles where Ash, in Mewtwo's body, shows his unique fighting style combined with Mewtwo's strength.
In a Pokemon fanfiction with Ash and Mewtwo, it could start with Ash encountering Mewtwo in an unexpected place. Maybe in a hidden forest where Mewtwo is observing the wild Pokemon. Ash, being his curious self, tries to approach Mewtwo. Mewtwo, initially hostile, realizes Ash's pure intentions and they start an unlikely friendship. This could lead to many adventures where Ash and Mewtwo face various challenges together, like battling against a new, powerful and evil Pokemon organization.
One idea could be that Mewtwo and Ash are forced to team up to save the Pokemon world from a new, powerful and evil threat. They start off distrusting each other due to their differences, but as they face challenges together, they begin to understand and respect one another.
One idea could be that Ash discovers a female Mewtwo in a hidden part of a forest. She's initially scared of humans but Ash manages to communicate with her using his bond with Pokemon. They go on a journey together to find a place where she can live in peace, away from those who might want to use her powers.
One idea could be that Ash discovers a wounded Mewtwo and nurses it back to health. As they spend time together, they form an unbreakable bond that challenges the way both Pokemon and humans interact. Another plot could involve Mewtwo using its powers to help Ash reach a new level of Pokemon training. For example, it could allow Ash to experience telepathic communication with his Pokemon, enhancing their battle strategies.
The unique personalities of the characters make it interesting. Ash is always eager to learn and grow, Mew is full of mystery and playfulness, and Mewtwo has its complex backstory and powerful abilities. When combined in a fanfiction, their interactions can be really engaging.
One interesting storyline could be that Ursula tries to steal Ash's Pikachu for her own collection. She might use her wits and some devious Pokemon to outsmart Ash. Another could be Ash and Ursula teaming up by accident to face a common enemy that threatens both of their goals. For example, a powerful and rogue Legendary Pokemon.